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公开(公告)号:US20220098134A1
公开(公告)日:2022-03-31
申请号:US17424105
申请日:2020-06-12
发明人: Honglin LI , Zhenjiang ZHAO , Rui WANG , Yinchu SHEN , Jianjun FU , Yufang XU , Xuhong QIAN , Qian JIAO , Shiliang LI
摘要: The present invention provides a compound as represented by formula I, or a pharmaceutically acceptable salt or ester, a prodrug, an optical isomer, a stereoisomer, or a solvate thereof. The compound provided by the present invention can be used for preparing drugs for preventing or treating hypertension, or hypertension-related diseases, or pulmonary hypertension, or pulmonary hypertension-related diseases. The compound provided by the present invention has a different mechanism from existing drugs for treating hypertension and pulmonary hypertension, thereby laying a new material foundation for the development of drugs for treating hypertension and pulmonary hypertension.