Invention Application
- Patent Title: COMPOSITIONS AND METHODS FOR SITE DIRECTED GENOMIC MODIFICATION
-
Application No.: US17503235Application Date: 2021-10-15
-
Publication No.: US20220135991A1Publication Date: 2022-05-05
- Inventor: Brent Brower-Toland , Andrei Y. Kouranov , Rosemarie Kuehn , Richard J. Lawrence , Ervin D. Nagy , Linda Rymarquis , Veena Veena
- Applicant: Monsanto Technology LLC
- Applicant Address: US MO St. Louis
- Assignee: Monsanto Technology LLC
- Current Assignee: Monsanto Technology LLC
- Current Assignee Address: US MO St. Louis
- Main IPC: C12N15/82
- IPC: C12N15/82

Abstract:
The disclosure provides novel corn, tomato, and soybean U6, U3, U2, U5, and 7SL snRNA promoters which are useful for CRISPR/Cas-mediated targeted gene modifications in plants. The disclosure also provides methods for use for U6, U3, U2, U5, and 7SL promoters in driving expression of sgRNA polynucleotides which function in a CRISPR/Cas system of targeted gene modification in plants. The disclosure also provides methods of genome modification by insertion of blunt-end DNA fragments at a site of genomic cleavage.
Public/Granted literature
- US11566254B2 Compositions and methods for site directed genomic modification Public/Granted day:2023-01-31
Information query
IPC分类: