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公开(公告)号:US20240229063A1
公开(公告)日:2024-07-11
申请号:US18541484
申请日:2023-12-15
Applicant: Monsanto Technology LLC
Inventor: Matthew Bauer , Sarah Brown , Robert Thomas Gaeta , Michael Edward Goley , Shirley Guo , Erin Lyn Hall , Andrei Kouranov , Clayton Tyler Larue , Mingsheng Peng , Linda Rymarquis , Oscar Cornelius Sparks, JR. , Xudong Ye
IPC: C12N15/82 , C12N9/22 , C12N15/11 , C12Q1/6827 , C12Q1/686 , C12Q1/6895 , G01N33/569 , G01N33/573
CPC classification number: C12N15/8274 , C12N9/22 , C12N15/111 , C12N15/8213 , C12Q1/6827 , C12Q1/686 , C12Q1/6895 , G01N33/56961 , G01N33/573 , C12N2310/20 , C12Q2600/13 , G01N2333/90206
Abstract: A transgenic corn event, Zm_CSM63715, is provided. Transgenic plant cells, plant parts, plants, seeds, progeny plants, and agricultural and commodity products containing event Zm_CSM63715 are also provided. Recombinant DNA molecules unique to the event Zm_CSM63715, and methods of using and detecting Zm_CSM63715 are also provided. Corn plants containing the event Zm_CSM63715 exhibit tolerance to PPO inhibitors.
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公开(公告)号:US20220135991A1
公开(公告)日:2022-05-05
申请号:US17503235
申请日:2021-10-15
Applicant: Monsanto Technology LLC
Inventor: Brent Brower-Toland , Andrei Y. Kouranov , Rosemarie Kuehn , Richard J. Lawrence , Ervin D. Nagy , Linda Rymarquis , Veena Veena
IPC: C12N15/82
Abstract: The disclosure provides novel corn, tomato, and soybean U6, U3, U2, U5, and 7SL snRNA promoters which are useful for CRISPR/Cas-mediated targeted gene modifications in plants. The disclosure also provides methods for use for U6, U3, U2, U5, and 7SL promoters in driving expression of sgRNA polynucleotides which function in a CRISPR/Cas system of targeted gene modification in plants. The disclosure also provides methods of genome modification by insertion of blunt-end DNA fragments at a site of genomic cleavage.
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公开(公告)号:US20240376489A1
公开(公告)日:2024-11-14
申请号:US18643394
申请日:2024-04-23
Applicant: Monsanto Technology LLC
Inventor: Brent Brower-Toland , Linda Rymarquis , Thomas L. Slewinski
Abstract: Provided are compositions and methods for altering TFL1 levels in soybean plants. Methods and compositions are also provided for altering the expression of genes related to the timing of terminal differentiation of stem tips through suppression, mutagenesis and/or editing of the TFL1 gene. Modified plant cells and plants having a suppression element or mutation reducing the expression or activity of a TFL1 gene are further provided comprising reduced TFL1 levels and improved characteristics, such as reduced plant height and increased lodging resistance.
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公开(公告)号:US20240209385A1
公开(公告)日:2024-06-27
申请号:US18596328
申请日:2024-03-05
Applicant: Monsanto Technology LLC
Inventor: Brent Brower-Toland , Andrei Y. Kouranov , Rosemarie Kuehn , Richard J. Lawrence , Ervin D. Nagy , Linda Rymarquis , Veena Veena
IPC: C12N15/82
CPC classification number: C12N15/8213 , C12N15/8216
Abstract: The disclosure provides novel corn, tomato, and soybean U6, U3, U2, U5, and 7SL snRNA promoters which are useful for CRISPR/Cas-mediated targeted gene modifications in plants. The disclosure also provides methods for us for U6, U3, U2, U5, and 7SL promoters in driving expression of sgRNA polynucleotides which function in a CRISPR/Cas system of targeted gene modification in plants. The disclosure also provides methods of genome modification by insertion of blunt-end DNA fragments at a site of genomic cleavage.
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公开(公告)号:US20230354762A1
公开(公告)日:2023-11-09
申请号:US18190739
申请日:2023-03-27
Applicant: Monsanto Technology LLC
Inventor: Steven Beach , Sivalinganna Manjunath , Linda Rymarquis , Thomas L. Slewinski , Xiaoyun Wu
CPC classification number: A01H6/4684 , A01H5/10 , C12N9/22 , C12N15/8262 , C12N2310/20
Abstract: Provided are compositions and methods for reducing, disrupting, or altering ZmDA1 activity in corn plants. Methods and compositions are also provided for producing modifications in the ZmDA1 gene through mutagenesis and/or editing. Modified plant cells and plants having a modification in the ZmDA1 gene are further provided comprising improved characteristics, such as increased yield.
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公开(公告)号:US20230340517A1
公开(公告)日:2023-10-26
申请号:US18190726
申请日:2023-03-27
Applicant: Monsanto Technology LLC
Inventor: Steven Beach , Sivalinganna Manjunath , Linda Rymarquis , Thomas L. Slewinski , Xiaoyun Wu
CPC classification number: C12N15/8261 , C12N9/22 , C12N15/11 , C12N15/8213 , C12N2310/20 , C12N2800/80
Abstract: Provided are compositions and methods for reducing, disrupting, or altering ZmGW2 activity in corn plants. Methods and compositions are also provided for producing modifications in the ZmGW2 gene through mutagenesis and/or editing. Modified plant cells and plants having a modification in the ZmGW2 gene are further provided comprising improved characteristics, such as increased yield.
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公开(公告)号:US20230313216A1
公开(公告)日:2023-10-05
申请号:US18190715
申请日:2023-03-27
Applicant: Monsanto Technology LLC
Inventor: Steven Beach , Sivalinganna Manjunath , Linda Rymarquis , Thomas L. Slewinski , Xiaoyun Wu
CPC classification number: C12N15/8243 , A01H6/4684 , A01H1/101
Abstract: Provided are compositions and methods for reducing, disrupting, or altering ZmDA2 activity in corn plants. Methods and compositions are also provided for producing modifications in the ZmDA2 gene through mutagenesis and/or editing. Modified plant cells and plants having a modification in the ZmDA2 gene are further provided comprising improved characteristics, such as increased yield.
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公开(公告)号:US10724047B2
公开(公告)日:2020-07-28
申请号:US15679699
申请日:2017-08-17
Applicant: MONSANTO TECHNOLOGY LLC
Inventor: Edwards M. Allen , Jayanand Boddu , Charles R. Dietrich , Alexander Goldshmidt , Miya Howell , Kevin R. Kosola , Sivalinganna Manjunath , Anil Neelam , Linda Rymarquis , Thomas L. Slewinski , Tyamagondlu V. Venkatesh , Huai Wang
IPC: C12N15/82 , C12N15/113
Abstract: The present disclosure provides compositions and methods for altering gibberellin (GA) content in corn or other cereal plants. Methods and compositions are also provided for altering the expression of genes related to gibberellin biosynthesis through suppression, mutagenesis and/or editing of specific subtypes of GA20 or GA3 oxidase genes. Modified plant cells and plants having a suppression element or mutation reducing the expression or activity of a GA oxidase gene are further provided comprising reduced gibberellin levels and improved characteristics, such as reduced plant height and increased lodging resistance, but without off-types.
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公开(公告)号:US11952578B2
公开(公告)日:2024-04-09
申请号:US18146434
申请日:2022-12-26
Applicant: Monsanto Technology LLC
Inventor: Brent Brower-Toland , Andrei Y. Kouranov , Rosemarie Kuehn , Richard J. Lawrence , Ervin D. Nagy , Linda Rymarquis , Veena Veena
IPC: C12N15/82
CPC classification number: C12N15/8213 , C12N15/8216
Abstract: The disclosure provides novel corn, tomato, and soybean U6, U3, U2, U5, and 7SL snRNA promoters which are useful for CRISPR/Cas-mediated targeted gene modifications in plants. The disclosure also provides methods for use for U6, U3, U2, U5, and 7SL promoters in driving expression of sgRNA polynucleotides which function in a CRISPR/Cas system of targeted gene modification in plants. The disclosure also provides methods of genome modification by insertion of blunt-end DNA fragments at a site of genomic cleavage.
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公开(公告)号:US11566254B2
公开(公告)日:2023-01-31
申请号:US17503235
申请日:2021-10-15
Applicant: Monsanto Technology LLC
Inventor: Brent Brower-Toland , Andrei Y. Kouranov , Rosemarie Kuehn , Richard J. Lawrence , Ervin D. Nagy , Linda Rymarquis , Veena Veena
IPC: C12N15/82
Abstract: The disclosure provides novel corn, tomato, and soybean U6, U3, U2, U5, and 7SL snRNA promoters which are useful for CRISPR/Cas-mediated targeted gene modifications in plants. The disclosure also provides methods for use for U6, U3, U2, U5, and 7SL promoters in driving expression of sgRNA polynucleotides which function in a CRISPR/Cas system of targeted gene modification in plants. The disclosure also provides methods of genome modification by insertion of blunt-end DNA fragments at a site of genomic cleavage.
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