A clock generation circuit includes a temperature compensation circuit and an oscillator. The temperature compensation circuit is configured to generate a temperature-compensated frequency selection code that varies depending on an operation temperature based on a difference between the operation temperature and a reference temperature and based on a temperature-independent frequency selection code that is fixed regardless of the operation temperature. The oscillator is configured to generate a clock signal that has an operation frequency that is based on the temperature-compensated frequency selection code, such that the operation frequency is uniform regardless of the operation temperature. Effects of the operation temperature may be reduced by generating the temperature-compensated frequency selection code that reflects the temperature characteristic of the oscillator using the output value of the temperature sensor and by controlling the oscillator using the temperature-compensated frequency selection code.