Various approaches for memory encryption management within an edge computing system are described. In an edge computing system deployment, a computing device includes capabilities to store and manage encrypted data in memory, through processing circuitry configured to: allocate memory encryption keys according to a data isolation policy for a microservice domain, with respective keys used for encryption of respective sets of data within the memory (e.g., among different tenants or tenant groups); and, share data associated with a first microservice to a second microservice of the domain. Such sharing may be based on the communication of an encryption key, used to encrypt the data in memory, from a proxy (such as a sidecar) associated with the first microservice to a proxy associated with the second microservice; and maintaining the encrypted data within the memory, for use with the second microservice, as accessible with the communicated encryption key.