Invention Application
- Patent Title: CHEMICAL COMPOUNDS AS INHIBITORS OF INTERLEUKIN-1 ACTIVITY
-
Application No.: US17686183Application Date: 2022-03-03
-
Publication No.: US20220306649A1Publication Date: 2022-09-29
- Inventor: Jeffrey A. STAFFORD , James M. VEAL , Lynnie Lin TRZOSS , Christopher MCBRIDE
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Main IPC: C07D498/04
- IPC: C07D498/04 ; A61P37/02
Abstract:
The present disclosure relates to novel sulfonylurea and sulfonyl thiourea compounds and related compounds and their use in treating a disease or condition responsive to modulation of cytokines such as IL-1β and IL-18, modulation of NLRP3 or inhibition of the activation of NLRP3 or related components of the inflammatory process.
Public/Granted literature
- US11702428B2 Chemical compounds as inhibitors of interleukin-1 activity Public/Granted day:2023-07-18
Information query
