Invention Application
- Patent Title: A Chemo-Enzymatic Process for the Preparation of Homopropargylic Alcohol
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Application No.: US17621052Application Date: 2020-06-17
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Publication No.: US20220333139A1Publication Date: 2022-10-20
- Inventor: Srivari CHANDRASEKHAR , Subhash GHOSH , Avula Shiva KRISHNA , Chada Raji REDDY , Gangarajula SUDHAKAR , Kumaraguru THENKRISHNAN , Srihari PABBARAJA , Prathama Satyendra MAINKAR , Rajesh NASAM
- Applicant: Council of Scientific and Industrial Research
- Applicant Address: IN New Delhi
- Assignee: Council of Scientific and Industrial Research
- Current Assignee: Council of Scientific and Industrial Research
- Current Assignee Address: IN New Delhi
- Priority: IN201911024666 20190621
- International Application: PCT/IN2020/050533 WO 20200617
- Main IPC: C12P7/04
- IPC: C12P7/04 ; C12P7/625 ; C12P41/00 ; C12N9/20

Abstract:
The present invention relates to an enzymatic process for preparation of optically pure enantiomers of homopropargylic alcohol compounds of formula I, which are useful intermediates for the synthesis of Halichondrin B and analogs. wherein, P is H or an alcohol protecting group, n is an integer ranging from 0-12.
Public/Granted literature
- US12247239B2 Chemo-enzymatic process for the preparation of homopropargylic alcohol Public/Granted day:2025-03-11
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