A computing device of a database system includes a plurality of processing modules, a computing device operating system, and an application specific operating system. The application specific operating system includes at least one custom instruction set that configures operation of a configurable set of processing modules of the plurality of processing modules based on generating, for each processing module of the configurable set of processing modules, a corresponding configuration signal indicating a selected instruction set of either the computing device operating system or the application specific operating system. Each processing module of the configurable set of processing modules operates in accordance with the selected instruction set based on the corresponding configuration signal.