Invention Publication
- Patent Title: GENE EDITING OF ANTICOAGULANT FACTORS
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Application No.: US18157329Application Date: 2023-01-20
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Publication No.: US20230190889A1Publication Date: 2023-06-22
- Inventor: DONG WOO SONG , BEOMSEOK CHOI , HYEKYUNG OH , NANYEONG GO , HYERIM LEE , KYU JUN LEE , UN GI KIM , JAEYOUNG LEE , JUNG MIN LEE
- Applicant: TOOLGEN INCORPORATED
- Applicant Address: KR SEOUL
- Assignee: TOOLGEN INCORPORATED
- Current Assignee: TOOLGEN INCORPORATED
- Current Assignee Address: KR SEOUL
- Priority: KR 20220008819 2022.01.20
- Main IPC: A61K38/46
- IPC: A61K38/46 ; C12N9/22 ; C12N15/11 ; C12N15/86 ; A61K31/7105 ; A61P7/04
Abstract:
The present disclosure relates to a composition for gene manipulation for artificially manipulating a blood coagulation inhibitory gene present in the genome of a cell to regulate a blood coagulation system. More particularly, the present invention relates to a composition for gene manipulation, which includes a guide nucleic acid capable of targeting a blood coagulation inhibitory gene, and an editor protein. Also, the present invention relates to a method of treating or improving coagulopathy using the composition for gene manipulation for artificially manipulating a blood coagulation inhibitory gene.
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