Invention Application
- Patent Title: PHOSPHORYLATED AKT-SPECIFIC CAPTURE AGENTS, COMPOSITIONS, AND METHODS OF USING AND MAKING
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Application No.: US17850743Application Date: 2022-06-27
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Publication No.: US20230019342A1Publication Date: 2023-01-19
- Inventor: James R. Heath , Arundhati Nag , Samir Das , Joseph O. Varghese , Ryan K. Henning
- Applicant: California Institute of Technology
- Applicant Address: US CA Pasadena
- Assignee: California Institute of Technology
- Current Assignee: California Institute of Technology
- Current Assignee Address: US CA Pasadena
- Main IPC: G01N33/574
- IPC: G01N33/574 ; C07K7/06 ; C07K7/08 ; C12Q1/48 ; G01N33/58
Abstract:
The present application provides stable peptide-based Akt capture agents and methods of use as detection and diagnosis agents and in the treatment of diseases and disorders. The application further provides methods of manufacturing Akt capture agents using iterative on-bead in situ click chemistry.
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