POLYMER NANOPARTICLE, METHOD FOR THE MANUFACTURE THEREOF, AND METHOD FOR INTRACELLULAR DELIVERY OF A CARGO
摘要:
A polymer nanoparticle includes a crosslinked polymer complex including a cargo encapsulated in a crosslinked polymer network; and a coating on the crosslinked polymer complex. The coating is derived from a cellular membrane. The polymer nanoparticles described herein can advantageously be used to deliver a cargo molecule (e.g., a nucleic acid) to a target location, for example upon administration to a subject in need of therapy.
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