- 专利标题: POLYMER NANOPARTICLE, METHOD FOR THE MANUFACTURE THEREOF, AND METHOD FOR INTRACELLULAR DELIVERY OF A CARGO
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申请号: US18197957申请日: 2023-05-16
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公开(公告)号: US20230372259A1公开(公告)日: 2023-11-23
- 发明人: Sankaran Thayumanavan
- 申请人: UNIVERSITY OF MASSACHUSETTS
- 申请人地址: US MA Boston
- 专利权人: UNIVERSITY OF MASSACHUSETTS
- 当前专利权人: UNIVERSITY OF MASSACHUSETTS
- 当前专利权人地址: US MA Boston
- 主分类号: A61K9/51
- IPC分类号: A61K9/51 ; C08L89/00 ; A61K38/46 ; A61K9/50 ; C12N15/113
摘要:
A polymer nanoparticle includes a crosslinked polymer complex including a cargo encapsulated in a crosslinked polymer network; and a coating on the crosslinked polymer complex. The coating is derived from a cellular membrane. The polymer nanoparticles described herein can advantageously be used to deliver a cargo molecule (e.g., a nucleic acid) to a target location, for example upon administration to a subject in need of therapy.
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