A microscope system for detecting a scan area within hematology slides in digital microscopy may include a scanning apparatus to scan a hematology sample, and a processor coupled to the scanning apparatus and a memory. The processor may be configured to execute instructions which may cause the system to receive a first image of the sample at a first resolution and determine a scan area of the sample to scan in response to the first image. The instructions may further cause the system to scan the scan area to generate an image of the scan area at a second resolution greater than the first resolution and classify a plurality of cells from the image of the scan area into cell data comprising a plurality of cell parameters. The instructions may also cause the microscope system to output the cell data. Various other systems and methods are provided.