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公开(公告)号:US20200041780A1
公开(公告)日:2020-02-06
申请号:US16338674
申请日:2017-10-26
Applicant: SCOPIO LABS LTD.
Inventor: Erez NA'AMAN , Michael Shimon ILUZ , Itai HAYUT
IPC: G02B21/36 , G02B21/00 , G06T7/11 , G06F16/955
Abstract: Access to microscope images while a sample is scanned or images are generated or uploaded can decrease an amount of time that a user waits to view a region of interest of an image. A processor can be configured to allow a remote user to access a portion of an image at full or partial resolution while other portions of the sample are being scanned, or while one or more images are generated or uploaded at full or partial resolution. A processor stored locally with the microscope can be configured to allow a remote user to access a completed scan over the internet prior to the scan being fully uploaded over a network such as the internet to a remote server. In some embodiments, a processor may be coupled to a microscope, a user device, or a remote server.
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公开(公告)号:US20230377144A1
公开(公告)日:2023-11-23
申请号:US18248553
申请日:2021-11-17
Applicant: SCOPIO LABS LTD.
Inventor: Ittai MADAR , Shahar KARNY , Eran SMALL , Erez NA'AMAN
CPC classification number: G06T7/0012 , G01N15/05 , G06T2207/10056 , G06T2207/30024 , G06T2207/30242 , G01N2015/055
Abstract: A microscope system for detecting a scan area within hematology slides in digital microscopy may include a scanning apparatus to scan a hematology sample, and a processor coupled to the scanning apparatus and a memory. The processor may be configured to execute instructions which may cause the system to receive a first image of the sample at a first resolution and determine a scan area of the sample to scan in response to the first image. The instructions may further cause the system to scan the scan area to generate an image of the scan area at a second resolution greater than the first resolution and classify a plurality of cells from the image of the scan area into cell data comprising a plurality of cell parameters. The instructions may also cause the microscope system to output the cell data. Various other systems and methods are provided.
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公开(公告)号:US20210392304A1
公开(公告)日:2021-12-16
申请号:US17304331
申请日:2021-06-18
Applicant: SCOPIO LABS LTD.
Inventor: Ben LESHEM , Eran SMALL , Itai HAYUT , Erez NA'AMAN , Eyal BEN-BASSAT
Abstract: A microscope for computational imaging may include an illumination source configured to illuminate a sample with a plurality of wavelengths, an image sensor, an objective lens to image the sample onto the image sensor, and a processor operatively coupled to the illumination assembly and the image sensor. The processor may be configured to acquire a first image dataset from the sample illuminated using a first set of illumination conditions at a first wavelength. The processor may also be configured to acquire a second image dataset from the sample illuminated using a second set of illumination conditions having a second number of illumination conditions at a second wavelength. The second set of illumination conditions comprises fewer illumination conditions than the first set in order to decrease acquisition time. The processor may be configured to combine the first and second image datasets into a computationally reconstructed image of the sample.
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公开(公告)号:US20210149170A1
公开(公告)日:2021-05-20
申请号:US17098099
申请日:2020-11-13
Applicant: SCOPIO LABS LTD.
Inventor: Ben LESHEM , Eran SMALL , Erez NA'AMAN
Abstract: A scanning microscope for z-stack acquisition may include, a stage to hold a sample, an illumination source to illuminate the sample, and an image capture device configured to capture multiple images of the sample within a field of view of the image capture device. The microscope may also include a lateral actuator for changing a relative lateral position between the image capture device and an imaged portion of the sample within the field of view of the image capture device for each of the images, and a focus actuator configured to adjust a focal distance between the sample and the image capture device between each of the images. The microscope may further include a processor connected to the lateral actuator and the focus actuator to move the sample laterally relative to the field of view and capture an area of the sample for each of multiple movement paths.
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公开(公告)号:US20200278530A1
公开(公告)日:2020-09-03
申请号:US16875721
申请日:2020-05-15
Applicant: SCOPIO LABS LTD.
Inventor: Ittai MADAR , Eran SMALL , Itai HAYUT , Erez NA'AMAN
Abstract: A microscope comprising an illumination assembly, an image capture device and a processor can be configured to selectively identify regions of a sample comprising artifacts or empty space. By selectively identifying regions of the sample that have artifacts or empty space, the amount of time to generate an image of the sample and resources used to generate the image can be decreased substantially while providing high resolution for appropriate regions of the computational image. The processor can be configured to change the imaging process in response to regions of the sample that comprises artifacts or empty space. The imaging process may comprise a higher resolution process to output higher resolution portions of the computational image for sample regions comprising valid sample material, and a lower resolution process to output lower resolution portions of the computational image for sample regions comprising valid sample material.
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公开(公告)号:US20240369584A1
公开(公告)日:2024-11-07
申请号:US18771065
申请日:2024-07-12
Applicant: SCOPIO LABS LTD.
Inventor: Itai HAYUT , Erez NA'AMAN , Eran SMALL
Abstract: A microscope system may comprise a plurality of microscope modules, a cassette for holding a plurality of slides, a slide loader configured to move the plurality of slides between the cassette and the plurality of microscope modules, and a processor coupled to the slide loader. The processor may be configured with instructions which, when executed, cause the slide loader to move a slide into or from a selected microscope module among the plurality of microscope modules. Various other methods, systems, and computer-readable media are also disclosed.
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公开(公告)号:US20240085688A1
公开(公告)日:2024-03-14
申请号:US18514050
申请日:2023-11-20
Applicant: SCOPIO LABS LTD.
Inventor: Ittai MADAR , Eran SMALL , Itai HAYUT , Erez NA'AMAN
CPC classification number: G02B21/367 , G02B21/0084 , G02B21/125
Abstract: A microscope comprising an illumination assembly, an image capture device and a processor can be configured to selectively identify regions of a sample comprising artifacts or empty space. By selectively identifying regions of the sample that have artifacts or empty space, the amount of time to generate an image of the sample and resources used to generate the image can be decreased substantially while providing high resolution for appropriate regions of the computational image. The processor can be configured to change the imaging process in response to regions of the sample that comprises artifacts or empty space. The imaging process may comprise a higher resolution process to output higher resolution portions of the computational image for sample regions comprising valid sample material, and a lower resolution process to output lower resolution portions of the computational image for sample regions comprising valid sample material.
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公开(公告)号:US20230005281A1
公开(公告)日:2023-01-05
申请号:US17931271
申请日:2022-09-12
Applicant: SCOPIO LABS LTD.
Inventor: Ben LESHEM , Eran SMALL , Itai HAYUT , Erez NA'AMAN , Eyal BEN-BASSAT
Abstract: A microscope for adaptive sensing may comprise an illumination assembly, an image capture device configured to collect light from a sample illuminated by the assembly, and a processor. The processor may be configured to execute instructions which cause the microscope to capture, using the image capture device, an initial image set of the sample, identify, in response to the initial image set, an attribute of the sample, determine, in response to identifying the attribute, a three-dimensional (3D) process for sensing the sample, and generate, using the determined 3D process, an output image set comprising more than one focal plane. Various other methods, systems, and computer-readable media are also disclosed.
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公开(公告)号:US20200302144A1
公开(公告)日:2020-09-24
申请号:US16851830
申请日:2020-04-17
Applicant: SCOPIO LABS LTD.
Inventor: Ben LESHEM , Eran SMALL , Itai HAYUT , Erez NA'AMAN , Eyal BEN-BASSAT
Abstract: A microscope for adaptive sensing may comprise an illumination assembly, an image capture device configured to collect light from a sample illuminated by the assembly, and a processor. The processor may be configured to execute instructions which cause the microscope to capture, using the image capture device, an initial image set of the sample, identify, in response to the initial image set, an attribute of the sample, determine, in response to identifying the attribute, a three-dimensional (3D) process for sensing the sample, and generate, using the determined 3D process, an output image set comprising more than one focal plane. Various other methods, systems, and computer-readable media are also disclosed.
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公开(公告)号:US20240160000A1
公开(公告)日:2024-05-16
申请号:US18559473
申请日:2022-05-26
Applicant: SCOPIO LABS LTD.
Inventor: Ben LESHEM , Erez NA'AMAN , Eran SMALL , Ben SARUSI
Abstract: A microscope system may be integrated with a coverslipping device. A method of preparing a microscope slide for imaging a sample on the microscope slide may include placing a transparent flowable material on the sample while the slide is supported with one or more linkages coupled to a processor, covering the sample with a coverslip, and placing the microscope slide on a microscope stage with the one or more linkages coupled to the slide and the processor. Various other systems and methods are provided.
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