- 专利标题: REPROGRAMMABLE ISCB NUCLEASES AND USES THEREOF
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申请号: US18032868申请日: 2021-10-22
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公开(公告)号: US20230392131A1公开(公告)日: 2023-12-07
- 发明人: Feng Zhang , Han Altae-Tran , Soumya Kannan , Fatma Esra Demircioglu
- 申请人: THE BROAD INSTITUTE, INC. , MASSACHUSETTS INSTITUTE OF TECHNOLOGY
- 申请人地址: US MA Cambridge
- 专利权人: THE BROAD INSTITUTE, INC.,MASSACHUSETTS INSTITUTE OF TECHNOLOGY
- 当前专利权人: THE BROAD INSTITUTE, INC.,MASSACHUSETTS INSTITUTE OF TECHNOLOGY
- 当前专利权人地址: US MA Cambridge
- 国际申请: PCT/US2021/056361 2021.10.22
- 进入国家日期: 2023-04-20
- 主分类号: C12N9/22
- IPC分类号: C12N9/22 ; C12N15/10 ; C12N15/63
摘要:
Systems, methods and compositions for targeting polynucleotides are detailed herein. In particular, engineered DNA-targeting systems comprising IscB polypeptides, novel IscB nucleases and reprogrammable targeting nucleic acid components and methods and application of use are provided.
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