- 专利标题： COMPOSITIONS AND METHODS FOR TREATING, AMELIORATING, AND/OR PREVENTING DISEASES OR DISORDERS CAUSED BY OR ASSOCIATED WITH DNASE1 AND/OR DNASE1L3 DEFICIENCY
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申请号： US17792101申请日： 2021-01-11
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公开(公告)号： US20230062096A1公开(公告)日： 2023-03-02
- 发明人: Paul Stabach , Demetrios Braddock
- 申请人： YALE UNIVERSITY
- 申请人地址： US CT New Haven
- 专利权人： YALE UNIVERSITY
- 当前专利权人： YALE UNIVERSITY
- 当前专利权人地址： US CT New Haven
- 国际申请： PCT/US21/12990 WO 20210111
- 主分类号： C07K16/24
- IPC分类号： C07K16/24 ; C12N9/22 ; C07K2/00 ; C07K14/00
摘要：
The present disclosure includes novel DNAse1 and/or DNAse1L3 constructs with improved in vivo half-lives, enzymatic stability, and/or developability properties.
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