Invention Application
- Patent Title: TECHNOLOGIES USEFUL FOR OLIGONUCLEOTIDE PREPARATION
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Application No.: US17439755Application Date: 2020-03-19
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Publication No.: US20230089442A1Publication Date: 2023-03-23
- Inventor: Pachamuthu Kandasamy , Mamoru Shimizu , David Charles Donnell Butler , Jayakanthan Kumarasamy , Gopal Reddy Bommineni , Mohammed Rowshon Alam , Sethumadhavan Divakaramenon , Bijay Tilak Bhattarai , Chandra Vargeese , Keith Andrew Bowman , Stephany Michelle Standley
- Applicant: Pachamuthu KANDASAMY , Mamoru SHIMIZU , David Charles Donnell BUTLER , Jayakanthan KUMARASAMY , Gopal Reddy BOMMINENI , Mohammed Rowshon ALAM , Sethumadhavan DIVAKARAMENON , Bijay Tilak BHATTARAI , Chandra VARGEESE , Keith Andrew BOWMAN , Stephany Michelle STANDLEY , WAVE LIFE SCIENCES LTD.
- Applicant Address: US MA Cambridge; US MA Cambridge; US MA Cambridge; US MA Cambridge; US MA Cambridge; US MA Cambridge; US MA Cambridge; US MA Cambridge; US MA Cambridge; US MA Cambridge; US MA Cambridge; SG Singapore
- Assignee: Pachamuthu KANDASAMY,Mamoru SHIMIZU,David Charles Donnell BUTLER,Jayakanthan KUMARASAMY,Gopal Reddy BOMMINENI,Mohammed Rowshon ALAM,Sethumadhavan DIVAKARAMENON,Bijay Tilak BHATTARAI,Chandra VARGEESE,Keith Andrew BOWMAN,Stephany Michelle STANDLEY,WAVE LIFE SCIENCES LTD.
- Current Assignee: Pachamuthu KANDASAMY,Mamoru SHIMIZU,David Charles Donnell BUTLER,Jayakanthan KUMARASAMY,Gopal Reddy BOMMINENI,Mohammed Rowshon ALAM,Sethumadhavan DIVAKARAMENON,Bijay Tilak BHATTARAI,Chandra VARGEESE,Keith Andrew BOWMAN,Stephany Michelle STANDLEY,WAVE LIFE SCIENCES LTD.
- Current Assignee Address: US MA Cambridge; US MA Cambridge; US MA Cambridge; US MA Cambridge; US MA Cambridge; US MA Cambridge; US MA Cambridge; US MA Cambridge; US MA Cambridge; US MA Cambridge; US MA Cambridge; SG Singapore
- International Application: PCT/US2020/023735 WO 20200319
- Main IPC: C07H1/02
- IPC: C07H1/02 ; C07H21/00 ; C07H19/04
Abstract:
Among other things, the present disclosure provides technologies for oligonucleotide preparation, particularly chirally controlled oligonucleotide preparation, which technologies provide greatly improved crude purity and yield, and significantly reduce manufacturing costs.
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