Invention Publication
- Patent Title: CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS
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Application No.: US18206937Application Date: 2023-06-07
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Publication No.: US20240067756A1Publication Date: 2024-02-29
- Inventor: David Spiegel , Ryan Murelli , Andrew Zhang
- Applicant: YALE UNIVERSITY
- Applicant Address: US CT New Haven
- Assignee: YALE UNIVERSITY
- Current Assignee: YALE UNIVERSITY
- Current Assignee Address: US CT New Haven
- The original application number of the division: US13173480 2011.06.30
- Main IPC: C07K16/44
- IPC: C07K16/44 ; A61K9/00 ; A61K31/4192 ; A61K45/06 ; A61K47/54 ; A61K47/55 ; A61K47/64 ; A61K47/68 ; C07D249/04 ; C07K16/30
Abstract:
The present invention relates to chimeric chemical compounds which are used to recruit antibodies to cancer cells, in particular, prostate cancer cells or metastasized prostate cancer cells. The compounds according to the present invention comprise an antibody binding terminus (ABT) moiety covalently bonded to a cell binding terminus (CBT) through a linker and optionally, a connector molecule.
Public/Granted literature
- US12084517B2 Chimeric small molecules for the recruitment of antibodies to cancer cells Public/Granted day:2024-09-10
Information query
