- 专利标题： REPROGRAMMABLE TNPB POLYPEPTIDES AND USE THEREOF
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申请号： US18271684申请日： 2022-01-25
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公开(公告)号： US20240084332A1公开(公告)日： 2024-03-14
- 发明人: Feng Zhang , Han Altae-Tran , Soumya Kannan , Suchita Nety
- 申请人： THE BROAD INSTITUTE, INC. , MASSACHUSETTS INSTITUTE OF TECHNOLOGY
- 申请人地址： US MA Cambridge
- 专利权人： THE BROAD INSTITUTE, INC.,MASSACHUSETTS INSTITUTE OF TECHNOLOGY
- 当前专利权人： THE BROAD INSTITUTE, INC.,MASSACHUSETTS INSTITUTE OF TECHNOLOGY
- 当前专利权人地址： US MA Cambridge
- 国际申请： PCT/US2022/013710 2022.01.25
- 进入国家日期： 2023-07-11
- 主分类号： C12N15/90
- IPC分类号： C12N15/90 ; C12N9/22 ; C12N15/11 ; C12N15/70 ; C12N15/74
摘要：
Systems, methods and composition for targeting polynucleotides are detailed herein. In particular, engineered DNA-targeting systems comprising novel TnpB polypeptides and a reprogrammable targeting nucleic acid component and methods and application of use are provided.
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