Invention Publication
- Patent Title: Artificial Sputum and Respiratory Epithelial Model for Bacterial Biofilms in the Respiratory Tract
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Application No.: US18495903Application Date: 2023-10-27
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Publication No.: US20240141285A1Publication Date: 2024-05-02
- Inventor: Jennifer M. Bomberger , Ananya Kapur
- Applicant: University of Pittsburgh - Of the Commonwealth System of Higher Education
- Applicant Address: US PA Pittsburgh
- Assignee: University of Pittsburgh - Of the Commonwealth System of Higher Education
- Current Assignee: University of Pittsburgh - Of the Commonwealth System of Higher Education
- Current Assignee Address: US PA Pittsburgh
- Main IPC: C12N1/20
- IPC: C12N1/20 ; C12N5/00
Abstract:
An airway model for culturing microbes such as bacteria Pseudomonas aeruginosa, is provided, comprising culturing the microbes in synthetic sputum media on an air-liquid interface culture of airway epithelial cells. The bacteria may be Pseudomonas aeruginosa, and the epithelial cells may be from a cystic fibrosis (CF) patient and/or comprise a mutation in CFTR found in CF patients.
Information query
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