Invention Publication
- Patent Title: ONCOLYTIC VIROTHERAPY WITH INDUCED ANTI-TUMOR IMMUNITY
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Application No.: US17773277Application Date: 2020-10-29
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Publication No.: US20240150787A1Publication Date: 2024-05-09
- Inventor: Shaun Xiaoliu ZHANG , Xinping FU
- Applicant: University of Houston System
- Applicant Address: US TX Houston
- Assignee: University of Houston System
- Current Assignee: University of Houston System
- Current Assignee Address: US TX Houston
- International Application: PCT/US20/57820 2020.10.29
- Date entered country: 2022-04-29
- Main IPC: C12N15/86
- IPC: C12N15/86 ; A61K35/763 ; A61P35/00 ; C07K14/195 ; C07K14/485 ; C07K16/32
Abstract:
Provided are improved oncolytic viruses with increased bystander cell killing and induced anti-tumor immunity. The oncolytic viruses include an oncolytic herpes virus backbone genetically modified to encode a tumor cell binding component and an immunoglobulin (Ig) binding component.
Information query
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