- 专利标题: MESENCHYMAL STEM CELLS EXPRESSING TNF-ALPHA RECEPTORS
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申请号: US18484347申请日: 2023-10-10
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公开(公告)号: US20240301356A1公开(公告)日: 2024-09-12
- 发明人: Alla DANILKOVITCH , Diane CARTER , Alicia Mildred TYRELL , Simon BUBNIC , Michelle MARCELINO , Rodney MONROY
- 申请人: MESOBLAST INTERNATIONAL SÁRL
- 申请人地址: CH Meyrin
- 专利权人: MESOBLAST INTERNATIONAL SÁRL
- 当前专利权人: MESOBLAST INTERNATIONAL SÁRL
- 当前专利权人地址: CH Meyrin
- 分案原申请号: US13402498 2012.02.22
- 主分类号: C12N5/0775
- IPC分类号: C12N5/0775 ; A61K35/12 ; A61K35/28
摘要:
Mesenchymal stem cells which express TNF-α receptor Type I in an amount of at least 13 pg/106 cells. Such mesenchymal stem cells inhibit the proliferation of lymphocytes and may be employed, in particular, in the treatment of graft-versus-host disease.
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