Invention Application
- Patent Title: QUATERNARY AMMONIUM CATION SUBSTITUTED COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS
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Application No.: US18404194Application Date: 2024-01-04
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Publication No.: US20240376073A1Publication Date: 2024-11-14
- Inventor: Sandra Marie Joseph GRALL-ULSEMER , Xingchun HAN , Joel Lukas KNECHT , Christian LERNER , Mingming LI , Yongqiang LIU , Patrizio MATTEI , Matthias NETTEKOVEN , Philippe PFLIEGER , Theodor STOLL , Jianhua WANG , Min WANG , Yongguang WANG , Song YANG , Chengang ZHOU
- Applicant: Hoffmann-La Roche Inc.
- Applicant Address: US NJ Little Falls
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Little Falls
- Priority: WOPCT/CN2021/104682 20210706
- Main IPC: C07D401/12
- IPC: C07D401/12 ; A61K31/4164 ; A61K31/4178 ; A61K31/427 ; A61K31/454 ; A61K31/4545 ; A61K31/496 ; A61K31/5355 ; A61P31/04 ; C07C53/06 ; C07C53/10 ; C07D233/90 ; C07D401/14 ; C07D403/12 ; C07D403/14 ; C07D413/12 ; C07D417/14 ; C07D487/04
Abstract:
The invention provides novel heterocyclic compounds having the general formula (I), and pharmaceutically acceptable salts thereof, wherein R1 to R6 are as described herein: Frther provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds as antibiotics for the treatment or prevention of bacterial infections and resulting diseases.
Information query
