发明授权
US4093709A Drug delivery devices manufactured from poly(orthoesters) and poly(orthocarbonates) 失效
由聚(原酸酯)和聚(原碳酸酯)制造的药物输送装置

Drug delivery devices manufactured from poly(orthoesters) and
poly(orthocarbonates)
摘要:
The invention concerns orthoester and orthocarbonate polymers having a repeating mer comprising a hydrocarbon radical and a symmetrical dioxycarbon unit of the general formula: ##STR1## WHEREIN R.sub.1 is a multivalent hydrocarbon radical, R.sub.2 and R.sub.3 are hydrocarbon radicals with at least one of R.sub.2 or R.sub.3 bonded to the dioxycarbon through an oxygen linkage, and which polymers are synthesized by reacting a polyol with an orthoester or orthocarbonate. The polymers are useful for making articles of manufacture, including devices and coatings for delivering beneficial agents.
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