发明授权
- 专利标题： Antibiotic Actinomadura-L-31 A, B
- 专利标题（中）： 抗生素Actinomadura-L-31 A，B
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申请号： US231359申请日： 1981-02-04
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公开(公告)号： US4328211A公开(公告)日： 1982-05-04
- 发明人: Hideo Sugawara , Yukio Miyazaki , Akio Seino
- 申请人： Hideo Sugawara , Yukio Miyazaki , Akio Seino
- 申请人地址： JPX Tokyo
- 专利权人： Kaken Chemical Co., Ltd.
- 当前专利权人： Kaken Chemical Co., Ltd.
- 当前专利权人地址： JPX Tokyo
- 优先权： JPX55-16647 19800215
- 主分类号： C07K14/195
- IPC分类号： C07K14/195 ; A61K35/74 ; A61P31/04 ; C07G11/00 ; C07K14/005 ; C07K14/41 ; C12P1/06 ; C12P21/00 ; C12R1/03 ; C12R1/465 ; A61K35/00
摘要：
Antibiotic Actinomadura-L-31 A has the characteristics as the hydrochloride salt:appearance: white or pale yellow powdermelting point: non-clear melting pointspecific rotation: [.alpha.].sub.D.sup.25 -34.degree. (C: 0.5, pH: 7.5 water)elementary analysis: (found) C: 51.71%; H: 6.23%; O: 21.03%; N: 13.94%; S: 5.82%; Cl: 1.17%constitutive aminoacids: aspartic acid; glutamic acid; glycin; valine; phenylalanine; histidine; leucine; tryptophanultraviolet absorption spectrum: FIG. 1, maximum absorption:280 nm: E.sub.1 cm.sup.1% =45.2290 nm: shoulder E.sub.1 cm.sup.1% =38infrared spectrum: FIG. 2, absorption (cm.sup.-1) 3350, 3050, 2950, 1660, 1530, 1430, 1395, 1340, 1255, 1235, 1100, 745, 700Antibiotic Actinomadura-L-31 B has the characteristics as the hydrochloride salt:appearance: white to pale yellow powdermelting point: non-clear melting pointspecific rotation: [.alpha.].sub.D.sup.25 -26.degree. (C: 0.5; pH: 7.5 water)elementary analysis: (found) C: 51.10%; H: 6.34%; O: 20.75% N: 14.81%; S: 5.91%; Cl: 1.08%constitutive aminoacids: aspartic acid; threonine; glutamic acid; proline; glycin; valine; phenylalanine; tryptophanultraviolet absorption spectrum: FIG. 3, maximum absorption:280 nm: E.sub.1 cm.sup.1% =44.8290 nm: shoulder E.sub.1 cm.sup.1% =37.3infrared spectrum: FIG. 4, absorption (cm.sup.-1) 3350, 3050, 2950, 1660, 1520, 1440, 1390, 1340, 1260, 1230, 1100, 745, 700.
公开/授权文献
- US6120581A Sulfur production process 公开/授权日：2000-09-19