发明授权
- 专利标题： Aminocyclopentane alkenoic acids and esters and pharmaceutical compositions
- 专利标题（中）： 氨基环戊烷链烯酸和酯和药物组合物
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申请号： US258721申请日： 1981-04-29
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公开(公告)号： US4342756A公开(公告)日： 1982-08-03
- 发明人: Eric W. Collington , Peter Hallett , Christopher J. Wallis , John Bradshaw , Norman F. Hayes
- 申请人： Eric W. Collington , Peter Hallett , Christopher J. Wallis , John Bradshaw , Norman F. Hayes
- 申请人地址： GB2
- 专利权人： Glaxo Group Limited
- 当前专利权人： Glaxo Group Limited
- 当前专利权人地址： GB2
- 优先权： GBX8014256 19800430
- 主分类号： B29C55/02
- IPC分类号： B29C55/02 ; A61K31/38 ; A61K31/381 ; A61K31/445 ; A61K31/535 ; A61K31/5375 ; A61K31/54 ; A61K31/55 ; A61P7/02 ; A61P9/08 ; A61P9/10 ; A61P11/00 ; A61P11/08 ; A61P27/02 ; A61P43/00 ; B29C49/00 ; B29C55/00 ; B29C55/18 ; B29K67/00 ; B29L7/00 ; C07C17/16 ; C07C29/147 ; C07C45/30 ; C07C405/00 ; C07D267/10 ; C07D295/02 ; C07D295/096 ; C07D295/112 ; C07D295/14 ; C07D295/155 ; C07D307/935 ; C07D309/12 ; C07D311/00 ; C07D333/12 ; C07D333/16 ; C07D333/22 ; C07D333/24 ; C07D333/54 ; C07D409/02 ; C07D413/04 ; D01F6/62
摘要：
Compounds are described of the formula ##STR1## (and their salts and solvates) in which: X is cis or trans --CH.dbd.CH--;R.sup.1 is C.sub.1-7 alkyl terminated by --COOR.sup.3 where R.sup.3 is H, C.sub.1-6 alkyl or C.sub.7-10 aralkyl;Y is a saturated heterocyclic amino group having 5-8 ring members; andR.sup.2 is C.sub.2-4 alkanoyl, C.sub.3-6 alkenyl (optionally substituted), C.sub.1-12 alkyl, or substituted or unsubstituted phenylalkyl, biphenylalkyl or naphthylalkyl.These compounds inhibit blood platelet aggregation and bronchoconstriction and may be formulated for use as antithrombotic and anti-asthmatic agents.
公开/授权文献
- US6082271A Folding table base 公开/授权日：2000-07-04