发明授权
- 专利标题： 7-Substituted benzopyranes and process for the preparation thereof
- 专利标题（中）： 7-取代的苯并吡喃及其制备方法
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申请号： US284573申请日： 1981-07-17
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公开(公告)号： US4391821A公开(公告)日： 1983-07-05
- 发明人: Dezso Korbonits , Mihaly Nogradi , Borbala Vermes nee Szluha , Janos Strelisky , Andras Wolfner , Gergely Heja , Gabor Kovacz , Jozsef Szegi , Sandor Virag
- 申请人： Dezso Korbonits , Mihaly Nogradi , Borbala Vermes nee Szluha , Janos Strelisky , Andras Wolfner , Gergely Heja , Gabor Kovacz , Jozsef Szegi , Sandor Virag
- 申请人地址： HUX Budapest
- 专利权人： Chinoin Gyogyszer es Vegyeszeti Termekek Gyara R.T.
- 当前专利权人： Chinoin Gyogyszer es Vegyeszeti Termekek Gyara R.T.
- 当前专利权人地址： HUX Budapest
- 优先权： HUX3001 19801216
- 主分类号： A61K31/35
- IPC分类号： A61K31/35 ; A61K31/352 ; A61P9/00 ; C07D311/22 ; C07D311/58 ; C07D311/60 ; C07D407/12
摘要：
The present invention relates to novel 7-substituted benzopyranes of formula (I), whereinR.sub.1 and R.sub.2 are hydrogen, alkyl of from 1 to 6 carbon atoms, hydroxyalkyl, alkenyl, cycloalkyl, phenylalkyl, dimethoxy-phenylalkyl, or R.sub.1 and R.sub.2 together with the joining nitrogen atom may represent a 5-7-membered heterocyclic ring,R.sub.3 is hydrogen, alkyl of from 1 to 4 carbon atoms or phenyl,R.sub.4 is hydrogen,R.sub.5 is hydrogen or phenyl, orR.sub.4 and R.sub.5 together may represent a bonding electron pair between the second and the third carbon atoms of the benzopyrane ring,R.sub.6 and R.sub.7 are hydrogen or they may represent an oxygen atom together,n is 1 or 2,with the proviso, that the pyrane ring may bear only one alkyl or phenyl substituent, and preparation process thereof.The novel compounds have valuable therapeutical effects, mainly in cardiotherapy.
公开/授权文献
- US5560518A Fluid delivery system 公开/授权日：1996-10-01
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