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公开(公告)号:US4391821A
公开(公告)日:1983-07-05
申请号:US284573
申请日:1981-07-17
申请人: Dezso Korbonits , Mihaly Nogradi , Borbala Vermes nee Szluha , Janos Strelisky , Andras Wolfner , Gergely Heja , Gabor Kovacz , Jozsef Szegi , Sandor Virag
发明人: Dezso Korbonits , Mihaly Nogradi , Borbala Vermes nee Szluha , Janos Strelisky , Andras Wolfner , Gergely Heja , Gabor Kovacz , Jozsef Szegi , Sandor Virag
IPC分类号: A61K31/35 , A61K31/352 , A61P9/00 , C07D311/22 , C07D311/58 , C07D311/60 , C07D407/12
CPC分类号: C07D407/12 , C07D311/22 , C07D311/58 , C07D311/60 , Y10S514/821
摘要: The present invention relates to novel 7-substituted benzopyranes of formula (I), whereinR.sub.1 and R.sub.2 are hydrogen, alkyl of from 1 to 6 carbon atoms, hydroxyalkyl, alkenyl, cycloalkyl, phenylalkyl, dimethoxy-phenylalkyl, or R.sub.1 and R.sub.2 together with the joining nitrogen atom may represent a 5-7-membered heterocyclic ring,R.sub.3 is hydrogen, alkyl of from 1 to 4 carbon atoms or phenyl,R.sub.4 is hydrogen,R.sub.5 is hydrogen or phenyl, orR.sub.4 and R.sub.5 together may represent a bonding electron pair between the second and the third carbon atoms of the benzopyrane ring,R.sub.6 and R.sub.7 are hydrogen or they may represent an oxygen atom together,n is 1 or 2,with the proviso, that the pyrane ring may bear only one alkyl or phenyl substituent, and preparation process thereof.The novel compounds have valuable therapeutical effects, mainly in cardiotherapy.
摘要翻译: 本发明涉及式(I)的新型7-取代苯并吡喃,其中R1和R2是氢,1-6个碳原子的烷基,羟基烷基,烯基,环烷基,苯基烷基,二甲氧基 - 苯基烷基或R1和R2连同 连接的氮原子可以表示5-7元杂环,R3是氢,1-4个碳原子的烷基或苯基,R4是氢,R5是氢或苯基,或R4和R5一起可以代表键合电子 苯并吡喃环的第二个和第三个碳原子之间的对,R6和R7是氢,或者它们可以一起代表氧原子,n是1或2,条件是吡喃环可以仅带有一个烷基或苯基取代基 ,及其制备方法。 新化合物具有重要的治疗作用,主要用于心脏治疗。
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公开(公告)号:US4166862A
公开(公告)日:1979-09-04
申请号:US470444
申请日:1974-05-16
申请人: Laszlo Feuer , Mihaly Nogradi , Agnes Gettsegen , Borbala Vermes , Janos Strelisky , Andras Wolfner , Lorant Farkas , Sandor Antus , Maria K. Toth
发明人: Laszlo Feuer , Mihaly Nogradi , Agnes Gettsegen , Borbala Vermes , Janos Strelisky , Andras Wolfner , Lorant Farkas , Sandor Antus , Maria K. Toth
IPC分类号: A23K1/16 , C07D311/36 , A61K31/35
CPC分类号: C07D311/36 , A23K20/121 , A23K20/137
摘要: An animal feed containing 0.00002 to 0.1% by weight of:2-methyl-7-methoxy-4'-nitroisoflavone,7-[hydroxyethoxy]-2-methylisoflavone,7-carbethoxy-2-methylisoflavone,7-ethoxyisoflavone,7-n-benzyloxy-2-methylisoflavone,7-p-nitrobenzyloxyisoflavone,7-p-nitrobenzyloxy-2-methylisoflavone,7-p-chlorobenzyloxyisoflavone,7-cetyloxy-2-methylisoflavone,7-(2-octyloxy)-isoflavone,7-benzyloxy-3',4'-dimethoxyisoflavone, and7-hexadecyloxyisoflavoneAs a weight-gain promoting anabolic ingredient.
摘要翻译: 含有0.00002至0.1重量%的动物饲料:
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