A pneumatic tire for high-speed running type motorcycles is disclosed, which comprises a carcass of a bias structure composed of at least two plies each containing organic fiber cords, a tread portion of rubber, a breaker disposed between the carcass and tread and composed of at least one ply containing organic fiber cords, and a side portion of rubber. In the pneumatic tire, the carcass and breaker are arranged in substantially parallel with each other, and the carcass has a cord angle of 26.degree.-36.degree. with respect to the equatorial plane of the tire, and the breaker has a cord angle of 0.degree.-25.degree. with respect to the equatorial plane and extends at a width corresponding to 30-200% of the tread width.