发明授权
- 专利标题： N-sulfamyl-3-halopropionamidines
- 专利标题（中）： N-磺酰基-3-卤代丙酰胺
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申请号： US905833申请日： 1986-09-10
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公开(公告)号： US4731479A公开(公告)日： 1988-03-15
- 发明人: Peter Bod , Kalman Harsanyi , Eva gai nee Csongor , Erik Bogsch , Eva Fekecs , Ferenc Trischler , Gyorgy Domany , Istvan Szabadkai , Bela Hegedus
- 申请人： Peter Bod , Kalman Harsanyi , Eva gai nee Csongor , Erik Bogsch , Eva Fekecs , Ferenc Trischler , Gyorgy Domany , Istvan Szabadkai , Bela Hegedus
- 申请人地址： HUX Budapest
- 专利权人： Richter Gedeon Vegyeszeti Gyar Rt.
- 当前专利权人： Richter Gedeon Vegyeszeti Gyar Rt.
- 当前专利权人地址： HUX Budapest
- 优先权： HUX3423/85 19850911
- 主分类号： C07C301/00
- IPC分类号： C07C301/00 ; C07C67/00 ; C07C303/34 ; C07C307/06 ; C07D277/48 ; C07C143/72
摘要：
The invention relates to new propionamidine derivatives of formula (I) ##STR1## wherein X is halogen,and to a process for their preparation. According to the invention compounds of the formula (I) are prepared by reacting a 3-halopropionitrile of the formula (III) ##STR2## wherein X is as defined above,with sulfamide of the formula (II) ##STR3## in the presence of a hydrogen halide. Compounds of the formula (I) are useful intermediates in the preparation of famotidine.
公开/授权文献
- US6106483A Apparatus for obtaining a cytology monolayer 公开/授权日：2000-08-22