发明授权
US4778925A New benzoic acid derivatives, as well as processes for their production
and their use as pharmaceuticals
失效
新的苯甲酸衍生物,以及其制备方法及其作为药物的用途
- 专利标题: New benzoic acid derivatives, as well as processes for their production and their use as pharmaceuticals
- 专利标题(中): 新的苯甲酸衍生物,以及其制备方法及其作为药物的用途
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申请号: US52917申请日: 1987-05-22
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公开(公告)号: US4778925A公开(公告)日: 1988-10-18
- 发明人: Helmut Grill , Friedemann Reiter , Michael Schliack , Roland Loser , Klaus Seibel
- 申请人: Helmut Grill , Friedemann Reiter , Michael Schliack , Roland Loser , Klaus Seibel
- 申请人地址: DEX Munich
- 专利权人: Klinge Pharma GmbH
- 当前专利权人: Klinge Pharma GmbH
- 当前专利权人地址: DEX Munich
- 主分类号: C07C51/347
- IPC分类号: C07C51/347 ; A61K31/19 ; A61K31/195 ; A61K31/235 ; A61P3/06 ; A61P9/10 ; C07C65/105 ; C07C65/34 ; C07C67/30 ; C07C67/303 ; C07C67/313 ; C07C69/76 ; C07C235/42 ; C07C235/84 ; C07C101/34
摘要:
Para substituted benzoic acid derivatives of general formula (1) ##STR1## and their physiologically compatible salts, where R.sup.1 may be H, isopropyl, t-butyl p0 X may be ##STR2## and R.sup.2 may be --OH, --OR', where R' is a linear or branched, saturated or unsaturated C.sub.1 to C.sub.3 alkylmoiety, or a --NHCH.sub.2 COOH-- group, have hypolipedemic activity. They may be obtained by known methods either from the corresponding unsaturated ketones or from saturated hydroxycompounds, where the esterified benzoic acid moiety may be saponified or converted to a carboxymethylamide.
公开/授权文献
- USD376278S Computer table 公开/授权日:1996-12-10
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