发明授权
- 专利标题： Immunoassay for human chorionic gonadotropin
- 专利标题（中）： 人绒毛膜促性腺激素免疫测定
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申请号： US72802申请日： 1987-07-14
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公开(公告)号： US4851356A公开(公告)日： 1989-07-25
- 发明人: Robert E. Canfield , Elmo G. Armstrong , Paul H. Ehrlich , Steven Birken
- 申请人： Robert E. Canfield , Elmo G. Armstrong , Paul H. Ehrlich , Steven Birken
- 申请人地址： NY New York
- 专利权人： The Trustees of Columbia University in the City of New York
- 当前专利权人： The Trustees of Columbia University in the City of New York
- 当前专利权人地址： NY New York
- 主分类号： G01N33/574
- IPC分类号： G01N33/574 ; G01N33/577 ; G01N33/76
摘要：
An immunoassay for detecting and measuring hCG in a sample includes an antibody directed to the carboxy terminal portion of the .beta. subunit of hCG and a monoclonal antibody directed to a determinant on hCG at a locus sufficiently remote from the carboxy terminal portion of the .beta. subunit of hCG that both antibodies can simultaneously bind to hCG, wherein at least one of the antibodies is delectable when both are bound to hCG.In a presently preferred embodiment, an immunoassay for hCG or hCB.beta. in urine includes a purified, labeled or detectable serum-derived antibody directed to the carboxy-terminal portion of the .beta. subunit of hCG and a matrix-bound monoclonal antibody directed to a locus on the .beta. subunit sufficiently remote from the carboxy-terminal portion that both antibodies can simultaneously bind to hCG or hCG.beta..
公开/授权文献
- US6119846A Collapsible gripper modules 公开/授权日：2000-09-19
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