发明授权
US4999358A (1,2,3,4-tetrahydro-9-acridinimino)cyclohexane carboxylic acid and
related compounds
失效
(1,2,3,4-四氢-9-吖啶亚氨基)环己烷羧酸及相关化合物
- 专利标题: (1,2,3,4-tetrahydro-9-acridinimino)cyclohexane carboxylic acid and related compounds
- 专利标题(中): (1,2,3,4-四氢-9-吖啶亚氨基)环己烷羧酸及相关化合物
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申请号: US371228申请日: 1989-06-26
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公开(公告)号: US4999358A公开(公告)日: 1991-03-12
- 发明人: Lawrence L. Martin , Joseph F. Payack , Helen H. Ong
- 申请人: Lawrence L. Martin , Joseph F. Payack , Helen H. Ong
- 申请人地址: NJ Somerville
- 专利权人: Hoechst-Roussel Pharmaceuticals Inc.
- 当前专利权人: Hoechst-Roussel Pharmaceuticals Inc.
- 当前专利权人地址: NJ Somerville
- 主分类号: A61K31/47
- IPC分类号: A61K31/47 ; A61K31/473 ; A61K31/535 ; A61P25/28 ; C07D219/10 ; C07D413/04
摘要:
There are described compounds of the formula, ##STR1## where X is hydrogen, loweralkyl, loweralkoxy or halogen;R when present is hydrogen, loweralkyl or arylloweralkyl;R.sub.1 is hydrogen, loweralkyl or arylloweralkyl; andR.sub.2 when present is hydrogen or loweralkyl;which compounds are useful for alleviating various memory dysfunctions characterized by a decreased cholinergic function such Alzheimer's disease.
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