发明授权
US5019500A IGF-I fusion proteins; protection of IGF-I from degradation by host cell
proteases; and processes for the production thereof
失效
IGF-I融合蛋白; 保护IGF-I免受宿主细胞蛋白酶的降解; 及其生产方法
- 专利标题： IGF-I fusion proteins; protection of IGF-I from degradation by host cell proteases; and processes for the production thereof
- 专利标题（中）： IGF-I融合蛋白; 保护IGF-I免受宿主细胞蛋白酶的降解; 及其生产方法
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申请号： US217885申请日： 1988-07-11
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公开(公告)号： US5019500A公开(公告)日： 1991-05-28
- 发明人: Ikuo Ueda , Mineo Niwa , Yoshimasa Saito , Susumu Sato , Hiroki Ono , Tadashi Kitaguchi
- 申请人： Ikuo Ueda , Mineo Niwa , Yoshimasa Saito , Susumu Sato , Hiroki Ono , Tadashi Kitaguchi
- 申请人地址： JPX Osaka
- 专利权人： Fujisawa Pharmaceutical Company, Ltd.
- 当前专利权人： Fujisawa Pharmaceutical Company, Ltd.
- 当前专利权人地址： JPX Osaka
- 优先权： GBX8407044 19840319; GBX8424197 19840925
- 主分类号： C07K1/12
- IPC分类号： C07K1/12 ; C07K14/00 ; C07K14/57 ; C07K14/575 ; C07K14/65 ; C07K19/00 ; C12N1/21 ; C12N15/09 ; C12N15/71 ; C12P21/02 ; C12R1/19
摘要：
IGF-I fused with a protective peptide, in which the protective peptide is a protein peptide and is used for the protection of IGF-I from degradation by protease in cells of E. coli is disclosed. Also disclosed are genes coding for the fused IGF-I's, plasmids containing the genes, and E. coli microorganisms transformed with the plasmids.
公开/授权文献
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