发明授权
US5169852A Method of suppressing appetite by administration of
tetrahydro-beta-carboline derivatives
失效
通过给予四氢-β-咔啉衍生物抑制食欲的方法
- 专利标题： Method of suppressing appetite by administration of tetrahydro-beta-carboline derivatives
- 专利标题（中）： 通过给予四氢-β-咔啉衍生物抑制食欲的方法
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申请号： US628692申请日： 1990-12-14
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公开(公告)号： US5169852A公开(公告)日： 1992-12-08
- 发明人: Jack D. Barchas , Glen R. Elliott , Peter I. Adriaenssens , Robert S. Bitner , Stephen S. Bowersox
- 申请人： Jack D. Barchas , Glen R. Elliott , Peter I. Adriaenssens , Robert S. Bitner , Stephen S. Bowersox
- 申请人地址： CA Menlo Park
- 专利权人： Neurex Corporation
- 当前专利权人： Neurex Corporation
- 当前专利权人地址： CA Menlo Park
- 主分类号： A61K31/44
- IPC分类号： A61K31/44
摘要：
Compounds of formula I are useful for suppressing appetite, and for altering macronutrient preferences, ##STR1## where the R.sub.2 -R.sub.9 substituents are so selected as to meet a defined quantitative structure activity relationship (QSAR) quantity relating to the partition coefficient of the compound, the net charge on the ring nitrogen, and the radical superfdelocalizability at the position-8 ring carbon.
公开/授权文献
- US5871757A Stabilization of polyunsaturates 公开/授权日：1999-02-16
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