发明授权
- 专利标题： Process for producing 2-carbon-substituted carbapenem derivatives
- 专利标题（中）： 制备2-碳取代的碳代青霉烯衍生物的方法
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申请号： US989150申请日： 1992-12-11
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公开(公告)号： US5258509A公开(公告)日： 1993-11-02
- 发明人: Susumu Nakagawa , Yoshiaki Kato , Hiroshi Fukatsu
- 申请人： Susumu Nakagawa , Yoshiaki Kato , Hiroshi Fukatsu
- 申请人地址： JPX Tokyo
- 专利权人： Banyu Pharmaceutical Co., Ltd.
- 当前专利权人： Banyu Pharmaceutical Co., Ltd.
- 当前专利权人地址： JPX Tokyo
- 优先权： JPX1-302529 19891121; JPX2-98597 19900413; JPX2-128446 19900518
- 主分类号： C07D477/02
- IPC分类号： C07D477/02 ; C07D477/14 ; C07D487/04
摘要：
A process for producing a 2-(unsubstituted or carbon-substituted)-1-carbapen-2-em-3-carboxylic acid derivative, which comprises reacting a 2-trifluoromethanesulfonyloxy-1-carbapen-2-em-3-carboxylic acid derivative or the 1-carbapen-2-em-3-carboxylic acid derivative derived from a 2-oxo-1-carbapenam-3-carboxylic acid derivative and trifluoromethanesulfonic anhydride, and a stannane derivative in an inert solvent in the presence of a palladium compound and a salt.
公开/授权文献
- US6029660A Substance delivery apparatus 公开/授权日：2000-02-29
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