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公开(公告)号:US5449672A
公开(公告)日:1995-09-12
申请号:US289547
申请日:1994-08-12
申请人: Susumu Nakagawa , Shinji Kato , Satoshi Murase , Osamu Okamoto , Ryuji Mitomo , Katsumi Yamamoto , Koji Yamada , Hiroshi Fukatsu
发明人: Susumu Nakagawa , Shinji Kato , Satoshi Murase , Osamu Okamoto , Ryuji Mitomo , Katsumi Yamamoto , Koji Yamada , Hiroshi Fukatsu
IPC分类号: A61K31/40 , A61K31/397 , A61P31/04 , C07D477/00 , C07D477/20 , C07D487/04
CPC分类号: C07D477/20 , Y02P20/55
摘要: A compound of the formula: ##STR1## wherein R.sup.1 is a hydrogen atom or a methyl group, R.sup.2 is a hydrogen atom or a negative charge, X is a group of --N(R.sup.3)R.sup.4 (wherein R.sup.3 is a lower alkyl group, and R.sup.4 is a hydrogen atom or a lower alkyl group) or a group of --N.sup.+ (R.sup.5)(R.sup.6)R.sup.7 (wherein each of R.sup.5, R.sup.6 and R.sup.7 which may be the same or different, is a lower alkyl group), and n is an integer of from 2 to 4; or a pharmaceutically acceptable salt or ester thereof.
摘要翻译: 下式的化合物:其中R1是氢原子或甲基,R2是氢原子或负电荷,X是-N(R3)R4(其中R3是低级) 烷基,R4为氢原子或低级烷基)或-N +(R5)(R6)R7(其中可相同或不同的R5,R6和R7各自为低级烷基) ),n为2〜4的整数。 或其药学上可接受的盐或酯。
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公开(公告)号:US5438054A
公开(公告)日:1995-08-01
申请号:US208046
申请日:1994-03-09
申请人: Susumu Nakagawa , Norikazu Ohtake , Fumio Nakano , Koji Yamada , Ryosuke Ushijima , Satoshi Murase , Hiroshi Fukatsu
发明人: Susumu Nakagawa , Norikazu Ohtake , Fumio Nakano , Koji Yamada , Ryosuke Ushijima , Satoshi Murase , Hiroshi Fukatsu
IPC分类号: C07D477/20 , A01N43/00 , A61K31/395 , C07D487/04
CPC分类号: C07D477/20
摘要: Carbapenem compounds of formula I and their pharmaceutically acceptable salts and esters are provided: ##STR1## wherein R, R.sup.1, R.sup.2, R.sup.3, p, q and r are as defined herein, which are useful as antibacterial agents.
摘要翻译: 提供式I的碳青霉烯化合物及其药学上可接受的盐和酯:其中R,R 1,R 2,R 3,p,q和r如本文所定义,其可用作抗菌剂。
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公开(公告)号:US5258509A
公开(公告)日:1993-11-02
申请号:US989150
申请日:1992-12-11
申请人: Susumu Nakagawa , Yoshiaki Kato , Hiroshi Fukatsu
发明人: Susumu Nakagawa , Yoshiaki Kato , Hiroshi Fukatsu
IPC分类号: C07D477/02 , C07D477/14 , C07D487/04
CPC分类号: C07D477/14 , C07D477/02
摘要: A process for producing a 2-(unsubstituted or carbon-substituted)-1-carbapen-2-em-3-carboxylic acid derivative, which comprises reacting a 2-trifluoromethanesulfonyloxy-1-carbapen-2-em-3-carboxylic acid derivative or the 1-carbapen-2-em-3-carboxylic acid derivative derived from a 2-oxo-1-carbapenam-3-carboxylic acid derivative and trifluoromethanesulfonic anhydride, and a stannane derivative in an inert solvent in the presence of a palladium compound and a salt.
摘要翻译: 2-(未取代或碳取代的)-1-碳代青霉-2-烯-3-羧酸衍生物的制备方法,其包括使2-三氟甲磺酰氧基-1-碳代青霉-2-烯-3-羧酸衍生物 或衍生自2-氧代-1-碳青霉烯-3-羧酸衍生物的1-碳代青霉-2-烯-3-羧酸衍生物和三氟甲磺酸酐,以及在惰性溶剂中在钯化合物存在下的锡烷衍生物 和盐。
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公开(公告)号:US5153188A
公开(公告)日:1992-10-06
申请号:US561846
申请日:1990-08-02
申请人: Susumu Nakagawa , Shinji Kato , Hiroshi Fukatsu
发明人: Susumu Nakagawa , Shinji Kato , Hiroshi Fukatsu
IPC分类号: C07D477/00 , A61K31/397 , A61K31/40 , A61P31/04 , C07D211/54 , C07D211/60 , C07D477/20
CPC分类号: C07D477/20 , C07D211/54 , C07D211/60 , Y02P20/55
摘要: A compound represented by the general formula (I): ##STR1## wherein R.sup.1 is a hydrogen atom or a methyl group; R.sup.2 and R.sup.3, which may be the same or different, each represents a hydrogen atom or a lower alkyl group, or taken together with the adjacent nitrogen atom, jointly represent a heterocyclic group selected from the group consisting of an aziridinyl group, an azetidinyl group, a pyrrolidinyl group, a piperidino group, a piperazinyl group, a 4-lower alkylpiperazinyl group, a morpholino group and a thiomorpholino group; and A is a single bond, a lower alkylene group, a lower alkenylene group or a lower alkynylene group; or a pharmaceutically acceptable salt or ester thereof.The compound of the general formula (I) and their salts or esters exhibit excellent antibacterial activity.
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公开(公告)号:US5049665A
公开(公告)日:1991-09-17
申请号:US414389
申请日:1989-09-29
IPC分类号: A61K31/545 , C07D501/26 , C07D501/59
CPC分类号: C07D501/59
摘要: A cephalosporin derivative having the formula: ##STR1## wherein R.sup.1 is a substituted amino group, X is an alkylene group, R.sup.2 is an aryl or heterocyclic group which may be substituted and R.sup.3 is a hydrogen atom, a negative charge or a residue of an ester which can form a pharmaceutically acceptable ester hydrolyzable in a living body; or a pharmaceutically acceptable salt thereof.
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公开(公告)号:US4574941A
公开(公告)日:1986-03-11
申请号:US599866
申请日:1984-04-13
CPC分类号: B21D43/105 , B65G47/914 , Y10S414/13 , Y10T74/18072
摘要: A workpiece conveying apparatus for a working machine including provided with a slider rail arranged vertically on the body of the workpiece conveying apparatus, a drive source, a parallel link consisting of the slider link which is fitted crossing at right angles to and slidably in said slider rail, a slider arm, a lower slider link carrying a work holder and a sub arm and being connected rotatably with each other, a rocking lever being connected to the middle portion of the slider arm rotatably and rocked by a driving mechanism at a predetermined angle, whereby the work holder can convey a workpiece into or out of the specified position along with the intentional locus settled selectively so as to reduce the operating range, and keep a continuous working operation of the working machine, resulting in the durability of the working machine.
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公开(公告)号:US4501352A
公开(公告)日:1985-02-26
申请号:US480035
申请日:1983-03-29
CPC分类号: B65G25/04 , Y10T74/18296
摘要: A work-conveying apparatus which conveys a work stably and without fail from the receipt of the work transferred from a conveying apparatus in the previous step to the transfer of the work to a conveying apparatus in the next step.
摘要翻译: 一种工件输送装置,其能够在接收到从前一步骤中的输送装置传送的作业中将工件稳定地传送到在下一步骤中将工件传送到输送装置的工作。
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公开(公告)号:US08046240B2
公开(公告)日:2011-10-25
申请号:US11563106
申请日:2006-11-24
申请人: Hiroshi Fukatsu , Muneyasu Kazuno , Akira Iwasa
发明人: Hiroshi Fukatsu , Muneyasu Kazuno , Akira Iwasa
IPC分类号: G06Q10/00
CPC分类号: G06Q50/24 , G06F19/00 , G06F19/321 , G06Q50/22 , G16H15/00
摘要: In issuing an order, a medical image diagnostic system acquires order issuance support information on the basis of a reference report or a reference image, which an order issuer uses as a basis of order creation. The medical image diagnostic system classifies the order issuance support information on the basis of a table and presents the order issuance support information using a predetermined order issuance support screen. For example, the order issuer selects desired conditions from the order issuance support screen presented to perform order issuance based on the reference report or the like.
摘要翻译: 在发布订单时,医用图像诊断系统基于订单发行者用作订单创建的基础的参考报告或参考图像来获取订单发行支持信息。 医疗图像诊断系统基于表格对订单发行支持信息进行分类,并使用预定的订单发行支持画面呈现订单发行支持信息。 例如,订单发行者基于参考报告等从所呈现的订单发行支持屏幕中选择所需条件以执行订单发行。
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公开(公告)号:US5100888A
公开(公告)日:1992-03-31
申请号:US549574
申请日:1990-07-06
申请人: Susumu Nakagawa , Yoshiaki Kato , Hiroshi Fukatsu
发明人: Susumu Nakagawa , Yoshiaki Kato , Hiroshi Fukatsu
IPC分类号: C07D477/00 , A61K31/397 , A61K31/40 , A61P31/04 , C07D207/24 , C07D477/20
CPC分类号: C07D477/20 , C07D207/24 , Y02P20/55
摘要: A compound represented by formula (I): ##STR1## wherein R.sup.1 represents a hydrogen atom or a methyl group; R.sup.2 and R.sup.3, which may be the same or different, each represents a hydrogen atom or a lower alkyl group; and R.sup.4 represents a carboxyl group, a lower alkoxycarbonyl group, a carbamoyl group, a lower alkylcarbamoyl group, a di-lower alkylcarbamoyl group, or a carbonyl group substituted with a heterocyclic group selected from the group consisting of an aziridinyl group, an azetidinyl group, a pyrrolidinyl group, a piperidino group, a morpholino group, a thio-morpholino group, a piperazinyl group, and a 4-lower alkyl-1-piperazinyl group, or a pharmaceutically acceptable salt or ester thereof. The compound of formula (I) and their salts or esters exhibit excellent antibacterial activity.
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公开(公告)号:US4918070A
公开(公告)日:1990-04-17
申请号:US161100
申请日:1988-02-26
IPC分类号: A61K31/545 , C07D501/26 , C07D501/59
CPC分类号: C07D501/59
摘要: A cephalosporin derivative having the formula: ##STR1## wherein R.sup.1 is a substituted amino group, X is an alkylene group, R.sup.2 is an aryl or heterocyclic group which may be substituted and R.sup.3 is a hydrogen atom, a negative charge or a residue of an ester which can form a pharmaceutically acceptable ester hydrolyzable in a living body; or a pharmaceutically acceptable salt thereof.
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