发明授权
- 专利标题： Red blood cell surrogate
- 专利标题（中）： 红细胞代孕
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申请号： US29773申请日： 1993-03-11
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公开(公告)号： US5306508A公开(公告)日： 1994-04-26
- 发明人: Nir Kossovsky , Andrew E. Gelman , Edward E. Sponsler
- 申请人： Nir Kossovsky , Andrew E. Gelman , Edward E. Sponsler
- 申请人地址： CA Oakland
- 专利权人： The Regents of the University of California
- 当前专利权人： The Regents of the University of California
- 当前专利权人地址： CA Oakland
- 主分类号： A61K9/50
- IPC分类号： A61K9/50 ; A61K9/00 ; A61K9/127 ; A61K9/16 ; A61K9/51 ; A61K31/00 ; A61K31/70 ; A61K31/74 ; A61K31/785 ; A61K33/44 ; A61K38/00 ; A61K38/16 ; A61K38/28 ; A61K38/40 ; A61K38/42 ; A61K38/48 ; A61K39/12 ; A61K39/21 ; A61K47/26 ; A61K47/48 ; A61K48/00 ; A61L31/10 ; A61P7/08 ; C07K14/05 ; C07K14/16 ; C12N11/14 ; C12N15/87 ; A61K9/14
摘要：
A red blood cell surrogate which is composed of a nanocrystalline core particle to which an oxygen carrier such as hemoglobin is bound. An oxygen carrier anchor coating is provided between the nanocrystalline core particle and the oxygen carrier in order to provide binding of the oxygen carrier to the nanocrystalline core particle without denaturing the oxygen carrier or otherwise destroying its oxygen carrying capacity. The nanocrystalline core particle with the oxygen carrier bound thereto is coated with an exterior layer of lipid.
公开/授权文献
- US5981539A Piperidine compounds as calcium channel blockers 公开/授权日：1999-11-09
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