发明授权
US5317009A Anti-HIV proteins GAP 31, DAP 30 and DAP 32 and therapeutic uses thereof
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抗HIV蛋白GAP 31,DAP 30和DAP 32及其治疗用途
- 专利标题: Anti-HIV proteins GAP 31, DAP 30 and DAP 32 and therapeutic uses thereof
- 专利标题(中): 抗HIV蛋白GAP 31,DAP 30和DAP 32及其治疗用途
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申请号: US749541申请日: 1991-08-26
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公开(公告)号: US5317009A公开(公告)日: 1994-05-31
- 发明人: Sylvia Lee-Huang , Hsiang-fu Kung , Paul L. Huang , Philip L. Huang , Peter Huang , Henry I. Huang , Hao-chia Chen
- 申请人: Sylvia Lee-Huang , Hsiang-fu Kung , Paul L. Huang , Philip L. Huang , Peter Huang , Henry I. Huang , Hao-chia Chen
- 申请人地址: NY New York MA Boston MD Bethesda
- 专利权人: New York University,American Biosciences, Inc.,National Institutes of Health
- 当前专利权人: New York University,American Biosciences, Inc.,National Institutes of Health
- 当前专利权人地址: NY New York MA Boston MD Bethesda
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; A61K39/395 ; A61K47/48 ; A61P31/12 ; A61P31/18 ; C07K1/18 ; C07K1/22 ; C07K1/30 ; C07K14/415 ; C07K16/00 ; C07K16/16 ; C12N15/09 ; C12P21/02 ; C07K13/00 ; C07K15/10 ; C07K15/14
摘要:
New proteins, termed GAP 31, obtainable from the seeds of Gelonium multiflorum, and DAP 30 and DAP 32, obtainable from the leaves or seeds of Dianthus caryophyllus, or the above proteins produced by recombinant means, are useful for treating HIV infections. In treating HIV infections, the protein is administered alone or in conjunction with other anti-HIV therapeutics. Also provided are processes for purifying the proteins, DNA sequences encoding the proteins, hosts expressing the proteins, recombinant DNA methods for expressing the proteins, and antibodies specific for the proteins.
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