发明授权
US5330892A MCC gene (mutated in colorectal cancer) used for diagnosis of cancer in
humans
失效
用于诊断人类癌症的MCC基因(在结肠直肠癌中突变)
- 专利标题: MCC gene (mutated in colorectal cancer) used for diagnosis of cancer in humans
- 专利标题(中): 用于诊断人类癌症的MCC基因(在结肠直肠癌中突变)
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申请号: US670611申请日: 1991-03-13
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公开(公告)号: US5330892A公开(公告)日: 1994-07-19
- 发明人: Bert Vogelstein , Kenneth W. Kinzler , Raymond White , Yusuke Nakamura
- 申请人: Bert Vogelstein , Kenneth W. Kinzler , Raymond White , Yusuke Nakamura
- 申请人地址: MD Baltimore UT Salt Lake City JPX
- 专利权人: The Johns Hopkins University,University of Utah,The Cancer Institute
- 当前专利权人: The Johns Hopkins University,University of Utah,The Cancer Institute
- 当前专利权人地址: MD Baltimore UT Salt Lake City JPX
- 主分类号: C07K16/00
- IPC分类号: C07K16/00 ; C07K14/00 ; C07K14/47 ; C07K14/82 ; C07K16/30 ; C07K16/32 ; C12N15/09 ; C12N15/12 ; C12P21/08 ; C12Q1/68 ; G01N33/53 ; G01N33/574 ; C12P19/34
摘要:
A new human gene termed MCC is disclosed. Methods and kits are provided for assessing mutations of the MCC gene in human tissues and body samples. Gross rearrangement and point mutations in MCC are observed in human tumor cells. MCC is expressed in most normal tissues. These results suggest that MCC is a tumor suppressor.
公开/授权文献
- US5774191A Chroma-key color range determination 公开/授权日:1998-06-30
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