发明授权
US5338840A DNA encoding glioma-derived growth factor having vascular endothelial
cell growth promoting activity
失效
编码具有血管内皮细胞生长促进活性的胶质瘤衍生生长因子的DNA
- 专利标题: DNA encoding glioma-derived growth factor having vascular endothelial cell growth promoting activity
- 专利标题(中): 编码具有血管内皮细胞生长促进活性的胶质瘤衍生生长因子的DNA
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申请号: US889547申请日: 1992-05-27
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公开(公告)号: US5338840A公开(公告)日: 1994-08-16
- 发明人: Marvin L. Bayne , Kenneth A. Thomas, Jr. , Gregory L. Conn
- 申请人: Marvin L. Bayne , Kenneth A. Thomas, Jr. , Gregory L. Conn
- 申请人地址: NJ Rahway
- 专利权人: Merck & Co., Inc.
- 当前专利权人: Merck & Co., Inc.
- 当前专利权人地址: NJ Rahway
- 主分类号: C12N15/09
- IPC分类号: C12N15/09 ; A61F2/06 ; A61K38/00 ; A61L27/00 ; A61P17/00 ; A61P43/00 ; C07K1/00 ; C07K1/16 ; C07K1/20 ; C07K1/22 ; C07K14/47 ; C07K14/52 ; C12N15/16 ; C12P21/00 ; C12P21/02 ; C12R1/19 ; C12R1/91 ; C07K13/00 ; A61K37/36
摘要:
Glioma-derived growth factor is purified from the culture media used to maintain mammalian glioma cells. The protein stimulates mitogenesis of mammalian vascular endothelial cells and is useful for the promotion of vascular development and repair. This unique growth factor is also useful in the promotion of tissue repair.
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