发明授权
US5366866A Method of diagnosing ovarian and endometrial cancer with monoclonal
antibodies OXA and OXB
失效
用单克隆抗体OXA和OXB诊断卵巢和子宫内膜癌的方法
- 专利标题: Method of diagnosing ovarian and endometrial cancer with monoclonal antibodies OXA and OXB
- 专利标题(中): 用单克隆抗体OXA和OXB诊断卵巢和子宫内膜癌的方法
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申请号: US879860申请日: 1992-05-06
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公开(公告)号: US5366866A公开(公告)日: 1994-11-22
- 发明人: Fengi J. Xu , Yinhua Yu , Robert C. Bast, Jr.
- 申请人: Fengi J. Xu , Yinhua Yu , Robert C. Bast, Jr.
- 申请人地址: NC Durham
- 专利权人: Duke University
- 当前专利权人: Duke University
- 当前专利权人地址: NC Durham
- 主分类号: C07K16/00
- IPC分类号: C07K16/00 ; C07K14/435 ; C07K14/705 ; C07K16/30 ; C12N15/02 ; C12P21/00 ; C12P21/08 ; C12R1/91 ; G01N33/531 ; G01N33/574 ; G01N33/577 ; G01N33/53 ; G01N33/567
摘要:
A method for detecting the presence of cancer employs monoclonal antibody OXA or OXB, antibodies which bind to the antigen bound by monoclonal antibody OXA or OXB, or fragments of the foregoing which bind to the antigen bound by monoclonal antibody OXA or OXB. The method comprises contacting a sample of a biological fluid from a subject with the antibody under conditions permitting the antibody to form a reaction product, and then detecting the presence or absence of the reaction product. The method is particularly useful for monitoring the progression of treatment in a patient previously diagnosed as having ovarian cancer. The method is also useful for detecting and monitoring endometrial cancer.
公开/授权文献
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