发明授权
US5384261A Very large scale immobilized polymer synthesis using mechanically
directed flow paths
失效
使用机械定向流动路径的非常大规模的固定化聚合物合成
- 专利标题: Very large scale immobilized polymer synthesis using mechanically directed flow paths
- 专利标题(中): 使用机械定向流动路径的非常大规模的固定化聚合物合成
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申请号: US796243申请日: 1991-11-22
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公开(公告)号: US5384261A公开(公告)日: 1995-01-24
- 发明人: James L. Winkler , Stephen P. A. Fodor , Christopher J. Buchko , Debra A. Ross , Lois Aldwin
- 申请人: James L. Winkler , Stephen P. A. Fodor , Christopher J. Buchko , Debra A. Ross , Lois Aldwin
- 申请人地址: ANX Curacao
- 专利权人: Affymax Technologies N.V.
- 当前专利权人: Affymax Technologies N.V.
- 当前专利权人地址: ANX Curacao
- 主分类号: B01J19/00
- IPC分类号: B01J19/00 ; C07B61/00 ; C07H21/00 ; C07K1/04 ; C40B40/06 ; C40B40/10 ; C40B60/14 ; G01N35/10 ; G01N33/543
摘要:
A method and device for forming large arrays of polymers on a substrate (401). According to a preferred aspect of the invention, the substrate is contacted by a channel block (407) having channels (409) therein. Selected reagents are flowed through the channels, the substrate is rotated by a rotating stage (403), and the process is repeated to form arrays of polymers on the substrate. The method may be combined with light-directed methodolgies.
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