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US5388572A Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same 失效
具有吸入活化活塞的干粉药物吸入器,以雾化剂量并输送相同剂量

Dry powder medicament inhalator having an inhalation-activated piston to
aerosolize dose and deliver same
摘要:
A dry powder inhalator for delivering a precise dose of a medicament contains a mesh disc impregnated with a series of spaced, medicament doses about the disc periphery. The inhalator is armed by manually retracting a finger pull extending downwardly from the bottom of the inhalator housing or rotating the bottom of the housing. The user inserts a mouthpiece on the housing into the mouth and inhales. This causes a chamber in the housing under a diaphragm to evacuate, thereby pulling the diaphragm down onto a knock out lever. The pivoting of the lever enables release of a piston into a cylinder which first compresses, and then dispenses a reduced volume of air at high pressure in a burst up through the medicament disc. When the burst of air hits the impregnated disc, the dose is forced out of the mesh's interstices, producing a cloud of the drug in its powdered form, which is inhaled by the user.
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