发明授权
US5478575A Polymers having benzeneboronic acid groups and insulin complexes of same
of a sugar response type
失效
具有苯硼酸基团的聚合物和具有糖响应型的相同的胰岛素复合物
- 专利标题: Polymers having benzeneboronic acid groups and insulin complexes of same of a sugar response type
- 专利标题(中): 具有苯硼酸基团的聚合物和具有糖响应型的相同的胰岛素复合物
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申请号: US37383申请日: 1993-03-26
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公开(公告)号: US5478575A公开(公告)日: 1995-12-26
- 发明人: Tsuyoshi Miyazaki , Yoshishige Murata , Daijiro Shiino , Kazunori Waki , Yasuhisa Sakurai , Teruo Okano , Kazunori Kataoka , Yoshiyuki Koyama , Masayuki Yokoyama , Shigeru Kitano
- 申请人: Tsuyoshi Miyazaki , Yoshishige Murata , Daijiro Shiino , Kazunori Waki , Yasuhisa Sakurai , Teruo Okano , Kazunori Kataoka , Yoshiyuki Koyama , Masayuki Yokoyama , Shigeru Kitano
- 申请人地址: JPX Tokyo
- 专利权人: Nippon Oil & Fats Co., Ltd.
- 当前专利权人: Nippon Oil & Fats Co., Ltd.
- 当前专利权人地址: JPX Tokyo
- 优先权: JPX1-270215 19891019; JPX2-241191 19900913; JPX2-241192 19900913
- 主分类号: A61K9/00
- IPC分类号: A61K9/00 ; A61K47/32 ; A61K47/36 ; A61K47/48 ; A61K38/28
摘要:
The present invention provides a polymer complex of a sugar response type having boronic acid groups in the polymer. Medicines may be contained or linked, preferably, the medicines have hydroxy groups. The polymer having boronic acid groups and the medicine having hydroxy groups may be linked by boronic acid ester bonds. The complex may also comprises polymers having boronic acid groups and polymers having hydroxy groups, and these polymers may be cross-linked.
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