发明授权
US5543552A Process for the prepartation of a substituted 2,5-diamino-3-hydroxyhexane
失效
预先取代的2,5-二氨基-3-羟基己烷的方法
- 专利标题: Process for the prepartation of a substituted 2,5-diamino-3-hydroxyhexane
- 专利标题(中): 预先取代的2,5-二氨基-3-羟基己烷的方法
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申请号: US419327申请日: 1995-04-10
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公开(公告)号: US5543552A公开(公告)日: 1996-08-06
- 发明人: Timothy L. Stuk , Michael S. Allen , Anthony R. Haight , M. Robert Leanna , Linda M. Lijewski , Laura Melcher , Howard E. Morton , Daniel S. Reno , Hing L. Sham , Thomas J. Sowin
- 申请人: Timothy L. Stuk , Michael S. Allen , Anthony R. Haight , M. Robert Leanna , Linda M. Lijewski , Laura Melcher , Howard E. Morton , Daniel S. Reno , Hing L. Sham , Thomas J. Sowin
- 申请人地址: IL Abbott Park
- 专利权人: Abbott Laboratories
- 当前专利权人: Abbott Laboratories
- 当前专利权人地址: IL Abbott Park
- 主分类号: C07C213/00
- IPC分类号: C07C213/00 ; C07C215/28 ; C07C225/16 ; C07C227/18 ; C07C229/36 ; C07C231/12 ; C07C233/35 ; C07C251/40 ; C07C255/27 ; C07C255/42 ; C07C269/06 ; C07C271/20 ; C07D209/44 ; C07D221/14 ; C07C261/00 ; C07C233/00 ; C07D209/04
摘要:
Intermediates and processes are disclosed which are useful for the preparation of a substantially pure compound of the formula: ##STR1## wherein R.sub.6 and R.sub.7 are each hydrogen or R.sub.6 and R.sub.7 are independently selected from ##STR2## wherein R.sub.a and R.sub.b are independently selected from hydrogen, loweralkyl and phenyl and R.sub.c, R.sub.d and R.sub.e are independently selected from hydrogen, loweralkyl, trifluoromethyl, alkoxy, halo and phenyl; and ##STR3## wherein the naphthyl ring is unsubstituted or substituted with one, two or three substitutents independently selected from loweralkyl, trifluoromethyl, alkoxy and halo; orR.sub.6 is as defined above and R.sub.7 is R.sub.7a OC(O)- wherein R.sub.7a is loweralkyl or benzyl; orR.sub.6 and R.sub.7 taken together with the nitrogen atom to which they are bonded are ##STR4## wherein R.sub.f, R.sub.g, R.sub.h and R.sub.i are independently selected from hydrogen, loweralkyl, alkoxy, halogen and trifluoromethyl and R.sub.8 is hydrogen or -C(O)R" wherein R" is loweralkyl, alkoxy, benzyloxy or phenyl wherein the phenyl ring is unsubstituted or substituted with one, two or three substituents independently selected from loweralkyl, trifluoromethyl, alkoxy and halo; or an acid addition salt thereof.
公开/授权文献
- US5075429A Monoazo-disperse dye compounds their production and their use 公开/授权日:1991-12-24
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