发明授权
US5545646A 4-bicyclically substituted dihydropyridines and their use in medicaments
失效
4-双环取代的二氢吡啶类及其在药物中的用途
- 专利标题: 4-bicyclically substituted dihydropyridines and their use in medicaments
- 专利标题(中): 4-双环取代的二氢吡啶类及其在药物中的用途
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申请号: US261585申请日: 1994-06-17
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公开(公告)号: US5545646A公开(公告)日: 1996-08-13
- 发明人: Alexander Straub , Siegfried Goldmann , J urgen Stoltefuss , Martin Bechem , Klaus Dembowsky , Rainer Gross , Siegbert Hebisch , Joachim H utter , Howard-Paul Rounding
- 申请人: Alexander Straub , Siegfried Goldmann , J urgen Stoltefuss , Martin Bechem , Klaus Dembowsky , Rainer Gross , Siegbert Hebisch , Joachim H utter , Howard-Paul Rounding
- 申请人地址: DEX Leverkusen
- 专利权人: Bayer Aktiengesellschaft
- 当前专利权人: Bayer Aktiengesellschaft
- 当前专利权人地址: DEX Leverkusen
- 优先权: DEX4321030.9 19930624
- 主分类号: A61K31/40
- IPC分类号: A61K31/40 ; A61K31/403 ; A61K31/4035 ; A61K31/404 ; A61K31/435 ; A61K31/44 ; A61K31/4427 ; A61K31/443 ; A61K31/4433 ; A61K31/455 ; A61K31/495 ; A61P9/08 ; A61P9/10 ; C07C45/71 ; C07C45/74 ; C07C47/546 ; C07C47/575 ; C07C49/835 ; C07C323/09 ; C07C323/62 ; C07D209/08 ; C07D209/44 ; C07D209/48 ; C07D211/84 ; C07D211/90 ; C07D215/14 ; C07D241/42 ; C07D241/48 ; C07D307/79 ; C07D311/04 ; C07D311/08 ; C07D311/18 ; C07D311/20 ; C07D311/22 ; C07D311/32 ; C07D311/42 ; C07D311/58 ; C07D311/76 ; C07D333/54 ; C07D333/62 ; C07D335/06 ; C07D401/04 ; C07D405/04 ; C07D409/04 ; C07D471/04 ; C07D491/04 ; C07D491/048 ; C07D495/04 ; C07D519/00 ; C07F9/24
摘要:
The invention relates to new 4-bicyclically substituted dihydropyridines of the general formula (I) ##STR1## in which R.sub.1 to R.sub.5 have the meaning given in the description, processes for their preparation and their use in medicaments, in particular in agents for the treatment of cardiovascular diseases.
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