发明授权
- 专利标题: Heterocyclic compounds
- 专利标题(中): 杂环化合物
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申请号: US218174申请日: 1994-03-28
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公开(公告)号: US5563141A公开(公告)日: 1996-10-08
- 发明人: Michael G. Wayne , Michael J. Smithers , John W. Rayner , Alan W. Faull , Robert J. Pearce , Andrew G. Brewster , Richard E. Shute , Stuart D. Mills , Peter W. R. Caulkett
- 申请人: Michael G. Wayne , Michael J. Smithers , John W. Rayner , Alan W. Faull , Robert J. Pearce , Andrew G. Brewster , Richard E. Shute , Stuart D. Mills , Peter W. R. Caulkett
- 申请人地址: GBX London
- 专利权人: Zeneca Limited
- 当前专利权人: Zeneca Limited
- 当前专利权人地址: GBX London
- 优先权: GBX9306451 19930329; GBX9325610 19931215
- 主分类号: A61K31/44
- IPC分类号: A61K31/44 ; A61K31/4402 ; A61K31/4406 ; A61K31/4409 ; A61K31/4418 ; A61K31/4427 ; A61K31/445 ; A61K31/4545 ; A61K31/47 ; A61K31/505 ; A61K31/5377 ; A61P7/02 ; A61P43/00 ; C07D213/74 ; C07D213/81 ; C07D215/14 ; C07D215/42 ; C07D239/42 ; C07D401/04 ; C07D401/12 ; C07D401/14 ; C07D405/12 ; C07D521/00 ; A61K31/495 ; C07D401/00 ; C07D403/00 ; C07D405/00
摘要:
A compound of the general formula(M.sup.1).sub.n --Q--(M.sup.2).sub.1-n --L--A Iwherein:n is 0 or 1;M.sup.1 is an amino group;Q is an aromatic heterocyclic group containing a basic nitrogen atom;M.sup.2 is an imino group;L is a template group; andA is an acidic group, or an ester or amide derivative thereof, or a sulphonamide group;and pharmaceutically acceptable salts and pro-drugs thereof, for use in the treatment of a disease in which platelet aggregation mediated by the binding of adhesion molecules to GPIIb-IIIa is involved. Novel compounds are also disclosed.
公开/授权文献
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