- 专利标题: Hydrolytic enzyme inhibitors/inactivators and methods for using same
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申请号: US388377申请日: 1995-02-14
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公开(公告)号: US5567597A公开(公告)日: 1996-10-22
- 发明人: Edward A. Dennis , William N. Washburn
- 申请人: Edward A. Dennis , William N. Washburn
- 申请人地址: CA Oakland
- 专利权人: The Regents of the University of California
- 当前专利权人: The Regents of the University of California
- 当前专利权人地址: CA Oakland
- 主分类号: A61K31/215
- IPC分类号: A61K31/215 ; A61K31/00 ; A61K31/22 ; A61K31/235 ; A61K31/66 ; A61K38/55 ; A61P29/00 ; C07C69/40 ; C07C69/708 ; C07C69/74 ; C07C69/75 ; C07C69/753 ; C07C69/76 ; C07C69/80 ; C07C237/22 ; C07C323/22 ; C07C327/20 ; C07C327/58 ; C07D311/16 ; C07F9/10 ; C12Q1/34 ; C12Q1/44 ; C07F9/02 ; C12N9/96 ; C12Q1/00
摘要:
The present invention provides compounds that function as hydrolytic enzyme inhibitors (inactivators) and substrates. These compounds are useful in assays to detect and measure levels of hydrolytic enzyme activity and are more particularly useful in treatment regimens for various disease states and conditions implicating the underlying specific hydrolytic enzyme. Examples of hydrolytic enzymes include, but are not limited to, phospholipases, lipases, esterases, proteases, etc.
公开/授权文献
- US4969974A Method for making electrode foil for an electrolyte capacitor 公开/授权日:1990-11-13
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