发明授权
- 专利标题： MCC protein and antibody
- 专利标题（中）： MCC蛋白和抗体
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申请号： US445186申请日： 1995-05-19
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公开(公告)号： US5576422A公开(公告)日： 1996-11-19
- 发明人: Bert Vogelstein , Kenneth W. Kinzler , Raymond White , Yusuke Nakamura
- 申请人： Bert Vogelstein , Kenneth W. Kinzler , Raymond White , Yusuke Nakamura
- 申请人地址： MD Baltimore UT Salt Lake City JPX
- 专利权人： The Johns Hopkins University,University of Utah,The Cancer Institute
- 当前专利权人： The Johns Hopkins University,University of Utah,The Cancer Institute
- 当前专利权人地址： MD Baltimore UT Salt Lake City JPX
- 主分类号： C07K16/00
- IPC分类号： C07K16/00 ; C07K14/00 ; C07K14/47 ; C07K14/82 ; C07K16/30 ; C07K16/32 ; C12N15/09 ; C12N15/12 ; C12P21/08 ; C12Q1/68 ; G01N33/53 ; G01N33/574
摘要：
A new human gene termed MCC is disclosed. Methods and kits are provided for assessing mutations of the MCC gene in human tissues and body samples. Gross rearrangement and point mutations in MCC are observed in human tumor cells. MCC is expressed in most normal tissues. These results suggest that MCC is a tumor suppressor. A MCC protein and antibody are disclosed.
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