发明授权
US5587173A Utilization of derivatives of 2,5 dihydroxyphenyl-carboxylic acid amides
and their salts in preparation of a cosmetic or dermatological
composition with a depigmenting action
失效
在制备具有脱色作用的化妆品或皮肤病学组合物中使用2,5二羟基苯基 - 羧酸酰胺及其盐的衍生物
- 专利标题: Utilization of derivatives of 2,5 dihydroxyphenyl-carboxylic acid amides and their salts in preparation of a cosmetic or dermatological composition with a depigmenting action
- 专利标题(中): 在制备具有脱色作用的化妆品或皮肤病学组合物中使用2,5二羟基苯基 - 羧酸酰胺及其盐的衍生物
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申请号: US465105申请日: 1995-06-05
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公开(公告)号: US5587173A公开(公告)日: 1996-12-24
- 发明人: Alex Junino , Alain LaGrange , Quang L. N'Guyen , Marie-Alix Bourboulon
- 申请人: Alex Junino , Alain LaGrange , Quang L. N'Guyen , Marie-Alix Bourboulon
- 申请人地址: FRX Paris
- 专利权人: L'Oreal
- 当前专利权人: L'Oreal
- 当前专利权人地址: FRX Paris
- 优先权: FRX9109029 19910717
- 主分类号: A61K8/30
- IPC分类号: A61K8/30 ; A61K8/00 ; A61K8/04 ; A61K8/11 ; A61K8/14 ; A61K8/33 ; A61K8/365 ; A61K8/37 ; A61K8/42 ; A61K8/49 ; A61Q17/04 ; A61Q19/00 ; A61Q19/02 ; C07C69/732 ; C07C69/734 ; C07C69/86 ; C07C69/92 ; C07C235/34 ; A61K7/42
摘要:
A cosmetic or dermatological composition with a depigmenting action comprises derivatives of 2,5-dihydroxyphenylcarboxylic acids, their homologs, and their salts, with the derivatives having the following structural formula: ##STR1## wherein: R.sub.1 represents OR.sub.5, OH, or ##STR2## R.sub.5 is a linear or branched C.sub.1 -C.sub.20 alkyl radical, a linear or branched C.sub.2 -C.sub.20 alkenyl radical, or a C.sub.1 -C.sub.20 alkyl radical substituted by one or more hydroxy or alkoxy groups;r' and r", identical or different, represent a hydrogen atom, a C.sub.1 -C.sub.20 alkyl radical, a C.sub.2 -C.sub.6 hydroxyalkyl radical, or a C.sub.3 -C.sub.6 polyhydroxyalkyl, or r' and r" taken together, with the nitrogen atom, form a heterocycle;the number of carbon atoms in the --(CH.sub.2).sub.n --COR.sub.1 chain is less than or equal to 21;R.sub.2 and R.sub.3, identical or different, represent a hydrogen atom, a linear or branched C.sub.1 -C.sub.4 alkyl radical, or a C.sub.1 -C.sub.4 alkoxy; R.sub.4 represents a hydrogen atom or a linear or branched C.sub.1 -C.sub.4 alkyl radical; andn is an integer from 0 to 20, provided that, when R.sub.2 and R.sub.3 represent a hydrogen atom, n is greater than or equal to 2.
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